Dynamic expression of tyrosine hydroxylase mRNA and protein in neurons of the striatum and amygdala of mice, and experimental evidence of their multiple …

M Bupesh, A Vicario, A Abellán, E Desfilis… - Brain Structure and …, 2014 - Springer
Emotional and motivational dysfunctions observed in Parkinson's disease, schizophrenia,
and drug addiction are associated to an alteration of the mesocortical and mesolimbic …

Expression of the paralogous tyrosine hydroxylase encoding genes th1 and th2 reveals the full complement of dopaminergic and noradrenergic neurons in zebrafish …

A Filippi, J Mahler, J Schweitzer… - Journal of Comparative …, 2010 - Wiley Online Library
The development of dopaminergic and noradrenergic neurons has received much attention
based on their modulatory effect on many behavioral circuits and their involvement in …

Early ontogeny of catecholaminergic cell lineage in brain and peripheral neurons monitored by tyrosine hydroxylase-lacZ transgene

JH Son, N Min, TH Joh - Molecular brain research, 1996 - Elsevier
As the first and rate limiting enzyme in the biosynthetic pathway for catecholamine (CA)
neurotransmitters, tyrosine hydroxylase (TH) is a specific phenotypic marker for CA cells in …

Targeted disruption of the tyrosine hydroxylase locus results in severe catecholamine depletion and perinatal lethality in mice

K Kobayashi, S Morita, H Sawada, T Mizuguchi… - Journal of Biological …, 1995 - ASBMB
Tyrosine 3-hydroxylase (TH, EC 1.14. 16.2) catalyzes the first and rate-limiting step of the
catecholamine biosynthetic pathway in the nervous and endocrine systems. The TH locus …

Postnatal development of the tyrosine hydroxylase-containing cell population within the rat locus coeruleus: topological organization andphenotypic plasticity

L Bezin, D Marcel, LI Debure, N Ginovart… - Journal of …, 1994 - Soc Neuroscience
The cellular phenotypic characteristics of tyrosine hydroxylase (TH) expression have been
studied within the rat locus coeruleus (LC) during postnatal development at six different …

Ontogenesis of tyrosine hydroxylase-immunopositive structures in the rat hypothalamus. An atlas of neuronal cell bodies

MV Ugrumov, J Taxi, A Tixier-Vidal, J Thibault… - Neuroscience, 1989 - Elsevier
The development of the catecholaminergic system in the hypothalamus and in the septal
region was studied in rats from the 12th fetal day until the 9th postnatal day …

Dynamics of tyrosine hydroxylase promoter activity during midbrain dopaminergic neuron development

N Matsushita, H Okada, Y Yasoshima… - Journal of …, 2002 - Wiley Online Library
Dopamine (DA)‐producing neurons in the ventral midbrain are generated from a specified
neuronal lineage and form selective axonal pathways that mediate multiple CNS functions …

Simplified CLARITY for visualizing immunofluorescence labeling in the developing rat brain

H Zheng, L Rinaman - Brain Structure and Function, 2016 - Springer
CLARITY is an innovative technological advance in which intact biological tissue is
transformed into a “nanoporous hydrogel-hybridized form”(Chung et al. 2013; Chung and …

CRE and TRE sequences of the rat tyrosine hydroxylase promoter are required for TH basal expression in adult mice but not in the embryo

C Trocmé, C Sarkis, JM Hermel… - European Journal of …, 1998 - Wiley Online Library
Tyrosine hydroxylase (TH), the rate‐limiting enzyme in the biosynthesis of catecholamine
neurotransmitters, is expressed in a restricted number of areas, and subject to numerous …

An optimized procedure for fluorescence-activated cell sorting (FACS) isolation of autonomic neural progenitors from visceral organs of fetal mice

DP Buehler, CB Wiese, SB Skelton… - JoVE (Journal of …, 2012 - jove.com
During development neural crest (NC)-derived neuronal progenitors migrate away from the
neural tube to form autonomic ganglia in visceral organs like the intestine and lower urinary …