[HTML][HTML] The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development

DW Kim, PW Washington, ZQ Wang, SH Lin… - Nature …, 2020 - nature.com
The hypothalamus is a central regulator of many innate behaviors essential for survival, but
the molecular mechanisms controlling hypothalamic patterning and cell fate specification …

[HTML][HTML] Regionalized differentiation of CRH, TRH, and GHRH peptidergic neurons in the mouse hypothalamus

N Morales-Delgado, B Castro-Robles, JL Ferran… - Brain Structure and …, 2014 - Springer
According to the updated prosomeric model, the hypothalamus is subdivided rostrocaudally
into terminal and peduncular parts, and dorsoventrally into alar, basal, and floor longitudinal …

The serotonergic anatomy of the developing human medulla oblongata: implications for pediatric disorders of homeostasis

HC Kinney, KG Broadbelt, RL Haynes… - Journal of chemical …, 2011 - Elsevier
Abstract The caudal serotonergic (5-HT) system is a critical component of a medullary
“homeostatic network” that regulates protective responses to metabolic stressors such as …

Structure of longitudinal brain zones that provide the origin for the substantia nigra and ventral tegmental area in human embryos, as revealed by cytoarchitecture and …

C Verney, N Zecevic, L Puelles - Journal of Comparative …, 2001 - Wiley Online Library
In a previous work, mapping early tyrosine hydroxylase (TH) expressing primordia in human
embryos, the tegmental origin of the substantia nigra (SN) and ventral tegmental area (VTA) …

Cell‐type profiling of the sympathetic nervous system using spatial transcriptomics and spatial mapping of mRNA

JC Kasemeier‐Kulesa, JA Morrison… - Developmental …, 2023 - Wiley Online Library
Background The molecular identification of neural progenitor cell populations that connect to
establish the sympathetic nervous system (SNS) remains unclear. This is due to technical …

Delayed plasticity of the mesolimbic dopamine system following neonatal 6‐OHDA lesions

PA Frohna, BS Neal‐Beliveau, JN Joyce - Synapse, 1997 - Wiley Online Library
In this study, we determined the ontogenetic profile (at postnatal days 7, 14, 35, and 90) of
tyrodine hydroxylase (TH) mRNA in the ventral mesencephalon, and the levels of TH …

Study of a fetal brain affected by a severe form of tyrosine hydroxylase deficiency, a rare cause of early parkinsonism

A Tristán-Noguero, H Díez, C Jou, M Pineda… - Metabolic brain …, 2016 - Springer
Tyrosine hydroxylase (TH) deficiency is an inborn error of dopamine synthesis. Two clinical
phenotypes have been described. The THD “B” phenotype produces a severe …

Generation of a Tph2/EGFP knockin mouse line for the study of the role of serotonin during the central nervous system development

S MIGLIARINI - 2008 - etd.adm.unipi.it
Serotonergic neurons constitute one of the most widely distributed neuronal systems in the
mammalian brain. These neurons, that are among the earliest to develop during …

The cellular and molecular landscape of hypothalamic patterning and differentiation

DW Kim, PW Washington, ZQ Wang, SH Lin, C Sun… - BioRxiv, 2019 - biorxiv.org
The hypothalamus is a central regulator of many innate behaviors that are essential for
survival, but the molecular mechanisms controlling hypothalamic patterning and cell fate …

[HTML][HTML] Dissection and culture of mouse dopaminergic and striatal explants in three-dimensional collagen matrix assays

ERE Schmidt, F Morello… - Journal of visualized …, 2012 - ncbi.nlm.nih.gov
Midbrain dopamine (mdDA) neurons project via the medial forebrain bundle towards several
areas in the telencephalon, including the striatum 1. Reciprocally, medium spiny neurons in …