Clinical significance and functional validation of PPA1 in various tumors
D Luo, G Wang, W Shen, S Zhao, W Zhou… - Cancer …, 2016 - Wiley Online Library
The aim of the study was to detect PPA 1 expression in various tumors and to investigate the
relationship between PPA 1 expression and clinicopathological parameters to further …
relationship between PPA 1 expression and clinicopathological parameters to further …
PPA1 promotes NSCLC progression via a JNK-and TP53-dependent manner
D Luo, D Liu, W Shi, H Jiang, W Liu, X Zhang, Y Bao… - Oncogenesis, 2019 - nature.com
Inorganic pyrophosphatase (PPA1) promotes tumor progression in several tumor types.
However, the underlying mechanism remains elusive. Here, we disclosed that PPA1 …
However, the underlying mechanism remains elusive. Here, we disclosed that PPA1 …
[HTML][HTML] PPA1 regulates tumor malignant potential and clinical outcome of colon adenocarcinoma through JNK pathways
P Wang, Y Zhou, Q Mei, J Zhao, L Huang, Q Fu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) represents one of the most prevalent malignancies and the third
leading cause of cancer death worldwide. Inorganic pyrophosphatase (PPA1) is an enzyme …
leading cause of cancer death worldwide. Inorganic pyrophosphatase (PPA1) is an enzyme …
Expression of inorganic pyrophosphatase (PPA1) correlates with poor prognosis of epithelial ovarian cancer
H Li, N Xiao, Z Li, Q Wang - The Tohoku journal of experimental …, 2017 - jstage.jst.go.jp
Ovarian serous carcinoma (OSC) is the most common epithelial ovarian cancer. Inorganic
pyrophosphatase (PPA1) catalyzes the hydrolysis of pyrophosphate to inorganic phosphate …
pyrophosphatase (PPA1) catalyzes the hydrolysis of pyrophosphate to inorganic phosphate …
Multi-omics pan-cancer analysis reveals the prognostic values and immunological functions of PPA2, with a spotlight on breast cancer
JN Zhang, BB Yang, LW Li, H Xu, B Wang… - Frontiers in …, 2024 - frontiersin.org
Background Recently, the role of inorganic pyrophosphatase 2 (PPA2) has been remaining
merely superficial in many tumors. Hence, the aim was to analyze the potential functions of …
merely superficial in many tumors. Hence, the aim was to analyze the potential functions of …
Downregulation of PPA2 expression correlates with poor prognosis of kidney renal clear cell carcinoma
W Zhu, H Jiang, S Xie, H Xiao, Q Liu, N Chen, P Wan… - PeerJ, 2021 - peerj.com
Background Kidney renal clear cell carcinoma (KIRC) is the most common subtype of kidney
cancer. Inorganic pyrophosphatase (PPA2) is an enzyme that catalyzes the hydrolysis of …
cancer. Inorganic pyrophosphatase (PPA2) is an enzyme that catalyzes the hydrolysis of …
[HTML][HTML] Silencing PPA1 inhibits human epithelial ovarian cancer metastasis by suppressing the Wnt/β-catenin signaling pathway
H Niu, W Zhou, Y Xu, Z Yin, W Shen, Z Ye, Y Liu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Inorganic pyrophosphatase (PPA1) activity is a key determinant of cellular inorganic
pyrophosphate levels, and its expression is correlated with growth of several solid tumors …
pyrophosphate levels, and its expression is correlated with growth of several solid tumors …
PPA1, an energy metabolism initiator, plays an important role in the progression of malignant tumors
S Wang, J Wei, S Li, Y Luo, Y Li, X Wang… - Frontiers in …, 2022 - frontiersin.org
Inorganic pyrophosphatase (PPA1) encoded by PPA1 gene belongs to Soluble
Pyrophosphatases (PPase) family and is expressed widely in various tissues of Homo …
Pyrophosphatases (PPase) family and is expressed widely in various tissues of Homo …
PPA1 promotes breast cancer proliferation and metastasis through PI3K/AKT/GSK3β signaling pathway
C Guo, S Li, A Liang, M Cui, Y Lou… - Frontiers in Cell and …, 2021 - frontiersin.org
Breast cancer is the most common malignancy among women. Inorganic pyrophosphatase
1 (PPA1) is a multifunctional protein involved in the development of several tumors …
1 (PPA1) is a multifunctional protein involved in the development of several tumors …
[HTML][HTML] Inorganic pyrophosphatase (PPA1) is a negative prognostic marker for human gastric cancer
Inorganic pyrophosphatase (PPA1) is an enzyme which has been found to be upregulated
in various tumors, yet its profile in gastrointestinal cancers has not systemically investigated …
in various tumors, yet its profile in gastrointestinal cancers has not systemically investigated …