The prognostic significance of intratumoral natural killer cells in patients with colorectal carcinoma

S Coca, J Perez‐Piqueras, D Martinez… - … Journal of the …, 1997 - Wiley Online Library
BACKGROUND Natural killer (NK) cells have a spontaneous cytotoxic capacity against
tumor cells. These cells represent a small proportion of human colon carcinoma‐infiltrating …

Prognostic significance of natural killer cell activity in patients with gastric carcinoma: a multivariate analysis

H Takeuchi, Y Maehara, E Tokunaga… - Official journal of the …, 2001 - journals.lww.com
OBJECTIVE: Natural cytotoxicity, mediated by natural killer (NK) cells, has been believed to
play an important role in inhibiting experimental tumor metastasis, and diminished NK cell …

Prognostic value of intratumoral natural killer cells in gastric carcinoma

S Ishigami, S Natsugoe, K Tokuda, A Nakajo, X Che… - Cancer, 2000 - Wiley Online Library
BACKGROUND Natural killer (NK) cells are a group of effector cells that act nonspecifically
against tumor cells. The correlation between intratumoral NK cell infiltration and …

[HTML][HTML] Prognostic value of peripheral blood natural killer cells in colorectal cancer

Y Tang, M Xie, K Li, J Li, Z Cai, B Hu - BMC gastroenterology, 2020 - Springer
Background The association between natural killer (NK) cells and survival in colorectal
cancer (CRC) patients remains controversial. This study aimed to clarify the prognostic value …

Natural killer cells are scarce in colorectal carcinoma tissue despite high levels of chemokines and cytokines

N Halama, M Braun, C Kahlert, A Spille, C Quack… - Clinical cancer …, 2011 - AACR
Purpose: Tumor infiltrating T lymphocytes in colorectal cancer (CRC) have prognostic
impact, but the role of natural killer (NK) cells in CRC tissue is unclear. The contribution of …

NK cells and T cells cooperate during the clinical course of colorectal cancer

G Sconocchia, S Eppenberger, GC Spagnoli… - …, 2014 - Taylor & Francis
Recent evidence suggests that natural killer (NK) cells are typically defective in infiltrating
solid tumors, with the exception of gastrointestinal stromal tumors (GIST). Interestingly …

Preoperative natural killer cell activity as a prognostic factor for distant metastasis following surgery for colon cancer

E Kondo, K Koda, N Takiguchi, K Oda, K Seike… - Digestive surgery, 2003 - karger.com
Background/Aims: To determine whether preoperative natural killer (NK) cell activity has any
prognostic significance in colon cancer patients. Methods: The study population consisted of …

[PDF][PDF] Prognostic significance of intratumoral natural killer cells in primary resected esophageal squamous cell carcinoma

J Hsia, J Chen, C Chen, C Hsu, J Miaw… - Chang Gung medical …, 2005 - academia.edu
Background: Natural killer (NK) cells are important effector cells in the defense against
tumors. The present study retrospectively examines the intratumoral NK cells in primary …

Natural killer cell activity in patients with hepatocellular carcinoma: a new prognostic indicator after hepatectomy

A Taketomi, M Shimada, K Shirabe, K Kajiyama… - Cancer, 1998 - Wiley Online Library
BACKGROUND Natural cytotoxicity mediated by natural killer (NK) cells is believed to play
an important role in host anticancer defense mechanisms. The aim of this study was to …

Increased intratumor Vα24-positive natural killer T cells: a prognostic factor for primary colorectal carcinomas

T Tachibana, H Onodera, T Tsuruyama, A Mori… - Clinical Cancer …, 2005 - AACR
Purpose: Human invariant natural killer T (NKT) cells are novel, distinct lymphocyte
populations with a restricted T-cell receptor repertoire (Vα24-Vβ11). They play a pivotal role …