Ropinirole used to treat Parkinson's disease highly targets the dopaminergic receptor D3
over the D2 receptor but although both are expressed in the kidneys the ropinirole potential …

Renal ischemia/reperfusion (I/R) injury is a major cause of acute kidney injury (AKI),
characterized by tubulointerstitial inflammation. Currently, progress in developing effective …

Background Renal ischemia-reperfusion (I/R) is one of the main causes of acute kidney
injury (AKI), for which there is currently no effective treatment. Recently, the interaction …

Background Recently, there has been an increasing clinical incidence of acute kidney injury
(AKI), which rapidly declines renal function and leads to massive tubular cell necrosis …

Cisplatin (CP) is a well-known anticancer drug used to effectively treat various kinds of solid
tumors. CP causes acute kidney injury (AKI) and unfortunately, there is no therapeutic …

Anisodamine protects against free radical-induced cellular damage. This study aimed to
investigate the protective effect of anisodamine on rhabdomyolysis-induced acute kidney …

Background Acute kidney injury (AKI) is a vital contributor to chronic kidney disease and
limited therapeutic options are existed to preserve the renal injury. The research presented …

Acute kidney injury (AKI) is a common complication of rhabdomyolysis (RM), a syndrome
characterized by skeletal muscle damage resulting in renal tubular oxidative stress …

Purpose To investigate the effect of baicalin on the reactive oxygen species (ROS)/NOD-like
receptor protein 3 (NLRP3)/Caspase-1/gasdermin-D (GSDMD) inflammasome pathway and …

Diabetic kidney disease (DKD) is an essential cause of end-stage renal disease. The
ongoing inflammatory response in the proximal tubule promotes the progression of DKD …