The ubiquity of RNA-seq has led to many methods that use RNA-seq data to analyze
variations in RNA splicing. However, available methods are not well suited for handling …

Pre-mRNA alternative splicing is a prevalent mechanism for diversifying eukaryotic
transcriptomes and proteomes. Regulated alternative splicing plays a role in many …

Alternative splicing is a major contributor to cellular diversity. Therefore the identification and
quantification of differentially spliced transcripts in genome-wide transcript analysis is an …

Despite the many approaches to study differential splicing from RNA-seq, many challenges
remain unsolved, including computing capacity and sequencing depth requirements. Here …

SpliceSeq is a resource for RNA-Seq data that provides a clear view of alternative splicing
and identifies potential functional changes that result from splice variation. It displays …

Analysis of RNA sequencing (RNA-Seq) data have highlighted the fact that most genes
undergo alternative splicing (AS) and that these patterns are tightly regulated. Many of these …

Alternative splicing is an important gene regulatory mechanism that dramatically increases
the complexity of the proteome. However, how alternative splicing is regulated and how …

The development of novel high-throughput sequencing (HTS) methods for RNA (RNA-Seq)
has provided a very powerful mean to study splicing under multiple conditions at …

Motivation: Understanding the occurrence and regulation of alternative splicing (AS) is a key
task towards explaining the regulatory processes that shape the complex transcriptomes of …

The emergence of single-cell RNA-seq (scRNA-seq) technology has made it possible to
measure gene expression variations at cellular level. This breakthrough enables the …