Epidermal growth factor receptor-targeted therapy for the treatment of non-small cell lung cancer: a review of phase II and III trials

HL Lu, GL Jie, YL Wu - Expert Opinion on Emerging Drugs, 2022 - Taylor & Francis
Introduction Epidermal growth factor receptor (EGFR) is one of the most common driver
gene mutations in non-small-cell lung cancer (NSCLC). EGFR-tyrosine kinase inhibitors …

Epidermal Growth Factor Receptor targeting in non-small cell lung cancer: revisiting different strategies against the same target

E Castanon, P Martin, C Rolfo, JP Fusco… - Current drug …, 2014 - ingentaconnect.com
Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibitors (TKIs) have changed
the paradigm of treatment in non-small cell lung cancer (NSCLC). The molecular biology …

Novel systemic therapies in the management of tyrosine kinase inhibitor-pretreated patients with epidermal growth factor receptor-mutant non-small-cell lung cancer

YS Li, GL Jie, YL Wu - Therapeutic Advances in Medical …, 2023 - journals.sagepub.com
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are the standard
first-line option for non-small-cell lung cancer (NSCLC) harboring active EGFR mutations …

Targeting epidermal growth factor receptor in non-small cell lung cancer: current advances and perspectives

A Italiano, B Besse, D Planchard, JC Soria - Bulletin du Cancer, 2007 - jle.com
EGFR tyrosine kinase inhibitors are currently included in the therapeutic armamentarium
against advanced NSCLC. However, many questions on the use of anti-EGFR treatment in …

Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of non-small cell lung cancer

L Kujtan, J Subramanian - Expert Review of Anticancer Therapy, 2019 - Taylor & Francis
Introduction: Epidermal growth factor receptor (EGFR) mutations are well-described drivers
of non-small cell lung cancer (NSCLC) and EGFR tyrosine kinase inhibitors (TKIs) have …

[HTML][HTML] Epidermal growth factor receptor tyrosine kinase inhibitors for non-small cell lung cancer

K Asami, S Atagi - World journal of clinical oncology, 2014 - ncbi.nlm.nih.gov
First-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs),
including gefitinib and erlotinib, have proven to be highly effective agents for advanced non …

Targeting epidermal growth factor receptor in the management of lung cancer

TSK Mok, K Lee, L Leung - Seminars in oncology, 2014 - Elsevier
The epidermal growth factor receptor (EGFR) mutation is a potent oncogenic driver that
accounts for carcinogenesis and tumor growth of pulmonary adenocarcinoma. Targeting …

RETRACTED ARTICLE: The Efficacy of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors for Molecularly Selected Patients with Non-Small Cell Lung …

J Liu, Z Sheng, Y Zhang, G Li - Targeted oncology, 2016 - Springer
Objective To determine the efficacy of first-generation epidermal growth factor receptor
tyrosine kinase inhibitors (EGFR-TKIs) in molecularly selected patients with advanced non …

[HTML][HTML] The role of anti-EGFR therapies in EGFR-TKI-resistant advanced non-small cell lung cancer

F Ciardiello, FR Hirsch, R Pirker, E Felip… - Cancer Treatment …, 2023 - Elsevier
Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are the current
recommended option for the first-line treatment of patients with EGFR-mutant non-small cell …

Efficacy of epidermal growth factor receptor inhibitors versus chemotherapy as second-line treatment in advanced non-small-cell lung cancer with wild-type EGFR: a …

N Zhao, X Zhang, H Yan, J Yang, Y Wu - Lung Cancer, 2014 - Elsevier
Background EGFR mutation status is closely related to the efficacy of EGFR-TKIs in
advanced non-small cell lung cancer (NSCLC). EGFR-TKIs have become the standard first …