Extracellular matrix component remodeling in respiratory diseases: what has been found in clinical and experimental studies?
Changes in extracellular matrix (ECM) components in the lungs are associated with the
progression of respiratory diseases, such as asthma, chronic obstructive pulmonary disease …
progression of respiratory diseases, such as asthma, chronic obstructive pulmonary disease …
The extracellular matrix–the under‐recognized element in lung disease?
The lung is composed of airways and lung parenchyma, and the extracellular matrix (ECM)
contains the main building blocks of both components. The ECM provides physical support …
contains the main building blocks of both components. The ECM provides physical support …
[HTML][HTML] Chronic lung diseases: entangled in extracellular matrix
JK Burgess, MC Harmsen - European Respiratory Review, 2022 - Eur Respiratory Soc
The extracellular matrix (ECM) is the scaffold that provides structure and support to all
organs, including the lung; however, it is also much more than this. The ECM provides …
organs, including the lung; however, it is also much more than this. The ECM provides …
Lung extracellular matrix and fibroblast function
ES White - Annals of the American Thoracic Society, 2015 - atsjournals.org
Extracellular matrix (ECM) is a tissue-specific macromolecular structure that provides
physical support to tissues and is essential for normal organ function. In the lung, ECM plays …
physical support to tissues and is essential for normal organ function. In the lung, ECM plays …
Extracellular matrix in lung development, homeostasis and disease
The lung's unique extracellular matrix (ECM), while providing structural support for cells, is
critical in the regulation of developmental organogenesis, homeostasis and injury-repair …
critical in the regulation of developmental organogenesis, homeostasis and injury-repair …
Extracellular matrix as a driver of progressive fibrosis
J Herrera, CA Henke… - The Journal of clinical …, 2018 - Am Soc Clin Investig
The extracellular matrix (ECM) is dynamically tuned to optimize physiological function. Its
major properties, including composition and mechanics, profoundly influence cell biology …
major properties, including composition and mechanics, profoundly influence cell biology …
Extracellular matrix remodelling in COPD
M Karakioulaki, E Papakonstantinou… - European Respiratory …, 2020 - Eur Respiratory Soc
The extracellular matrix (ECM) of the lung plays several important roles in lung function, as it
offers a low resistant pathway that allows the exchange of gases, provides compressive …
offers a low resistant pathway that allows the exchange of gases, provides compressive …
Disorders of lung matrix remodeling
HA Chapman - The Journal of clinical investigation, 2004 - Am Soc Clin Investig
A set of lung diseases share the tendency for the development of progressive fibrosis
ultimately leading to respiratory failure. This review examines the common pathogenetic …
ultimately leading to respiratory failure. This review examines the common pathogenetic …
Extracellular matrix injury during lung inflammation
EJ Campbell, RM Senior, HG Welgus - Chest, 1987 - journal.chestnet.org
Irreversible abnormalities of lung architecture are hallmarks of many acute and chronic
diseases. Lung cavities in gram-negative bacterial pneumonias and pulmonary tuberculosis …
diseases. Lung cavities in gram-negative bacterial pneumonias and pulmonary tuberculosis …
Matrix remodeling in pulmonary fibrosis and emphysema
T Kulkarni, P O'Reilly, VB Antony, A Gaggar… - American journal of …, 2016 - atsjournals.org
Pulmonary fibrosis and emphysema are chronic lung diseases characterized by a
progressive decline in lung function, resulting in significant morbidity and mortality. A …
progressive decline in lung function, resulting in significant morbidity and mortality. A …