[PDF][PDF] The case for normothermic machine perfusion in liver transplantation

CDL Ceresa, D Nasralla, CC Coussios… - Liver …, 2018 - Wiley Online Library
In recent years, there has been growing interest in normothermic machine perfusion (NMP)
as a preservation method in liver transplantation. In most countries, because of a donor …

[HTML][HTML] Normothermic machine preservation of the liver: state of the art

CDL Ceresa, D Nasralla, W Jassem - Current transplantation reports, 2018 - Springer
Abstract Purpose of Review This review aims to introduce the concept of normothermic
machine perfusion (NMP) and its role in liver transplantation. By discussing results from …

[PDF][PDF] The 24‐hour normothermic machine perfusion of discarded human liver grafts

T Vogel, JG Brockmann, A Quaglia… - Liver …, 2017 - Wiley Online Library
Donor organ shortage necessitates use of less than optimal donor allografts for
transplantation. The current cold storage preservation technique fails to preserve marginal …

[HTML][HTML] Liver transplantation after ex vivo normothermic machine preservation: a phase 1 (first-in-man) clinical trial

R Ravikumar, W Jassem, H Mergental, N Heaton… - American Journal of …, 2016 - Elsevier
The number of donor organs suitable for liver transplantation is restricted by cold
preservation and ischemia–reperfusion injury. We present the first patients transplanted …

[HTML][HTML] Preliminary single-center Canadian experience of human normothermic ex vivo liver perfusion: results of a clinical trial

M Bral, B Gala-Lopez, D Bigam, N Kneteman… - American Journal of …, 2017 - Elsevier
After extensive experimentation, outcomes of a first clinical normothermic machine perfusion
(NMP) liver trial in the United Kingdom demonstrated feasibility and clear safety, with …

[HTML][HTML] Normothermic machine perfusion (NMP) of the liver–current status and future perspectives

CJ van Beekum, TO Vilz, TR Glowka… - Annals of …, 2021 - ncbi.nlm.nih.gov
A shortage of available organs for liver transplantation has led transplant surgeons and
researchers to seek for innovative approaches in hepatoprotection and improvement of …

Clinical implementation of prolonged liver preservation and monitoring through normothermic machine perfusion in liver transplantation

B Cardini, R Oberhuber, M Fodor, T Hautz… - …, 2020 - journals.lww.com
Background. Normothermic machine perfusion (NMP) bears the potential for significant
prolongation of liver preservation before transplantation. Although safety and feasibility have …

Long-term outcomes after normothermic machine perfusion in liver transplantation—Experience at a single North American center

J Hefler, D Leon-Izquierdo, BA Marfil-Garza… - American Journal of …, 2023 - Elsevier
Normothermic machine perfusion (NMP) has emerged as a valuable tool in the preservation
of liver allografts before transplantation. Randomized trials have shown that replacing static …

[HTML][HTML] Machine perfusion of the liver: a review of clinical trials

N Serifis, R Matheson, D Cloonan, CG Rickert… - Frontiers in …, 2021 - frontiersin.org
Although efforts have been made by transplant centers to increase the pool of available
livers by extending the criteria of liver acceptance, this practice creates risks for recipients …

[HTML][HTML] Normothermic liver machine perfusion as a dynamic platform for regenerative purposes: What does the future have in store for us?

B Lascaris, VE de Meijer, RJ Porte - Journal of Hepatology, 2022 - Elsevier
Liver transplantation has become an immense success; nevertheless, far more recipients
are registered on waiting lists than there are available donor livers for transplantation. High …