Methenamine hippurate to prevent recurrent urinary tract infections in older women: protocol for a randomised, placebo-controlled trial (ImpresU)

SR Heltveit-Olsen, PD Sundvall, R Gunnarsson… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Methenamine hippurate is a urinary antiseptic used as preventive treatment for
recurrent urinary tract infections (UTIs) in some Scandinavian countries. However, the …

Use of methenamine hippurate to prevent urinary tract infections in community adult women: a systematic review and meta-analysis

M Bakhit, N Krzyzaniak, J Hilder, J Clark… - British Journal of …, 2021 - bjgp.org
Background Urinary tract infections (UTIs) are often treated with antibiotics and are a source
of antibiotic overuse. Aim To systematically review randomised controlled trials (RCTs) of …

Preventive effect of methenamine in women with recurrent urinary tract infections–a case–control study

L Rui, M Lindbaek, S Gjelstad - Scandinavian Journal of Primary …, 2022 - Taylor & Francis
Background Urinary tract infection (UTI) is the most common bacterial infection in women. In
Norwegian general practice, methenamine has been prescribed for many years as long …

Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial

C Harding, H Mossop, T Homer, T Chadwick, W King… - bmj, 2022 - bmj.com
Objective To test and compare the efficacy of methenamine hippurate for prevention of
recurrent urinary tract infections with the current standard prophylaxis of daily low dose …

ALternatives To prophylactic Antibiotics for the treatment of Recurrent urinary tract infection in women (ALTAR): study protocol for a multicentre, pragmatic, patient …

R Forbes, A Ali, A Abouhajar, C Brennand, H Brown… - Trials, 2018 - Springer
Background At least half of all adult women will experience infective cystitis (urinary tract
infection: UTI) at least once in their life and many suffer from repeated episodes. Recurrent …

[HTML][HTML] Methenamine hippurate compared with antibiotic prophylaxis to prevent recurrent urinary tract infections in women: the ALTAR non-inferiority RCT

C Harding, T Chadwick, T Homer, J Lecouturier… - 2022 - ncbi.nlm.nih.gov
Background: Daily, low-dose antibiotic prophylaxis is the current standard care for women
with recurrent urinary tract infection. Emerging antimicrobial resistance is a global health …

Evaluation of methenamine for urinary tract infection prevention in older adults: a review of the evidence

A Chwa, K Kavanagh, SA Linnebur… - … advances in drug …, 2019 - journals.sagepub.com
Urinary tract infections (UTI) commonly occur in older adults and can lead to more severe,
life-threatening infections. Physiological factors that change with age are thought to …

An oldie but a goodie: Methenamine as a nonantibiotic solution to the prevention of recurrent urinary tract infections

C Gu, AL Ackerman - PLoS Pathogens, 2023 - journals.plos.org
Urinary tract infections (UTIs) are one of the most common adult bacterial infections. The
global burden of UTIs has nearly doubled in the last 30 years with more than 400 million …

Effectiveness of methenamine for UTI prevention in older adults

MS Snellings, SA Linnebur… - Annals of …, 2020 - journals.sagepub.com
Background: Methenamine is a drug used for the prevention of lower urinary tract infections
(UTIs). However, efficacy has not been established in older adults or patients with varying …

The resurgence of methenamine hippurate in the prevention of recurrent UTIs in women-a systematic review

S Kale, BK Somani - Current Opinion in Urology, 2023 - journals.lww.com
The resurgence of methenamine hippurate in the prevention of... : Current Opinion in
Urology The resurgence of methenamine hippurate in the prevention of recurrent UTIs in …