Safety and immunogenicity of a respiratory syncytial virus prefusion F vaccine when coadministered with a tetanus, diphtheria, and acellular pertussis vaccine

JT Peterson, AM Zareba, D Fitz-Patrick… - The Journal of …, 2022 - academic.oup.com
Background Prevention of respiratory syncytial virus (RSV) disease in infants is an unmet
vaccine need, and maternal immunization is a potential strategy to address this need. This …

A randomized, controlled, observer-blinded phase 1 study of the safety and immunogenicity of a respiratory syncytial virus vaccine with or without alum adjuvant

JM Langley, N Aggarwal, A Toma… - The Journal of …, 2017 - academic.oup.com
Background Respiratory syncytial virus (RSV) is a leading cause of childhood bronchiolitis
and pneumonia, particularly in early infancy. Immunization of pregnant women could boost …

A randomized phase 1/2 study of a respiratory syncytial virus prefusion F vaccine

EE Walsh, AR Falsey, DA Scott… - The Journal of …, 2022 - academic.oup.com
Background Protection against human respiratory syncytial virus (RSV) remains an unmet
need potentially addressable by maternal immunization. This phase 1/2 study evaluated a …

Prefusion F protein–based respiratory syncytial virus immunization in pregnancy

EAF Simões, KJ Center, ATN Tita… - … England Journal of …, 2022 - Mass Medical Soc
Background Respiratory syncytial virus (RSV), a major cause of illness and death in infants
worldwide, could be prevented by vaccination during pregnancy. The efficacy …

Safety and immunogenicity of 3 formulations of an investigational respiratory syncytial virus vaccine in nonpregnant women: results from 2 phase 2 trials

J Beran, JD Lickliter, TF Schwarz… - The Journal of …, 2018 - academic.oup.com
Background Respiratory syncytial virus (RSV) causes bronchiolitis and pneumonia in
neonates and infants. RSV vaccination during pregnancy could boost preexisting …

Respiratory syncytial virus prefusion F subunit vaccine: first approval of a maternal vaccine to protect infants

YY Syed - Pediatric Drugs, 2023 - Springer
Pfizer is developing a bivalent respiratory syncytial virus (RSV) prefusion F subunit vaccine
(RSVpreF; ABRYSVO™) for preventing RSV illness in infants and individuals aged≥ 60 …

Bivalent prefusion F vaccine in pregnancy to prevent RSV illness in infants

B Kampmann, SA Madhi, I Munjal… - … England Journal of …, 2023 - Mass Medical Soc
Background Whether vaccination during pregnancy could reduce the burden of respiratory
syncytial virus (RSV)–associated lower respiratory tract illness in newborns and infants is …

Respiratory Syncytial Virus Prefusion F Vaccination: Antibody Persistence and Revaccination

EE Walsh, AR Falsey, AM Zareba… - The Journal of …, 2024 - academic.oup.com
Background Respiratory syncytial virus (RSV) causes substantial respiratory disease.
Bivalent RSV prefusion F (RSVpreF) vaccine is licensed in≥ 60-year-olds. RSVpreF was …

RSV prefusion f protein–based maternal vaccine—preterm birth and other outcomes

I Dieussaert, J Hyung Kim, S Luik, C Seidl… - … England Journal of …, 2024 - Mass Medical Soc
Background Vaccination against respiratory syncytial virus (RSV) during pregnancy may
protect infants from RSV disease. Efficacy and safety data on a candidate RSV prefusion F …

[HTML][HTML] Safety and immunogenicity of a respiratory syncytial virus fusion glycoprotein F subunit vaccine in healthy adults: results of a phase 1, randomized, observer …

G Leroux-Roels, F De Boever, C Maes, TLA Nguyen… - Vaccine, 2019 - Elsevier
Introduction Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory
tract infections in infants. An investigational vaccine using an engineered recombinant RSV …