[HTML][HTML] Mirtazapine reduces adipocyte hypertrophy and increases glucose transporter expression in obese mice

CF Wu, PH Hou, FC Mao, YC Su, CY Wu, WC Yang… - Animals, 2020 - mdpi.com
Simple Summary Mirtazapine, a tetracyclic antidepressant, acts through noradrenergic and
specific serotonergic systems. Consequently, it was recently applied in major depressive …

[HTML][HTML] Risperidone exacerbates glucose intolerance, nonalcoholic fatty liver disease, and renal impairment in obese mice

HP Tsai, PH Hou, FC Mao, CC Chang… - International Journal of …, 2021 - mdpi.com
Risperidone, a second-generation antipsychotic drug used for schizophrenia treatment with
less-severe side effects, has recently been applied in major depressive disorder treatment …

[HTML][HTML] Weight-gain independent effect of mirtazapine on fasting plasma lipids in healthy men

K Lechner, S Heel, M Uhr, T Dose, F Holsboer… - Naunyn-Schmiedeberg's …, 2023 - Springer
Abstract Treatment with mirtazapine, a widely prescribed antidepressant, has been linked to
weight gain and dyslipidemia. Whether dyslipidemia occurs secondary to increased appetite …

Effect of the antiobesity agent sibutramine in obese-diabetic ob/ob mice

C Day, CJ Bailey - International journal of obesity, 1998 - nature.com
BACKGROUND: Sibutramine is a reuptake inhibitor of 5-hydroxytryptamine and
noradrenaline, being developed as a treatment for obesity. OBJECTIVE: To investigate the …

Risperidone-induced metabolic dysfunction is attenuated by Curcuma longa extract administration in mice

F Auger, F Martin, O Pétrault, J Samaillie… - Metabolic Brain …, 2018 - Springer
Antipsychotics, such as risperidone, increase food intake and induce alteration in glucose
and lipid metabolism concomitantly with overweight and body fat increase, these biological …

Myricetin-induced brown adipose tissue activation prevents obesity and insulin resistance in db/db mice

T Hu, X Yuan, G Wei, H Luo, HJ Lee, W Jin - European journal of nutrition, 2018 - Springer
Purpose Myricetin, a dietary flavonoid, is effective in the treatment of obesity and insulin
resistance by increasing glucose transport and lipogenesis in adipocyte and diminishing …

Quinacrine attenuates diet-induced obesity by inhibiting adipogenesis via activation of AMPK signaling

X Li, J Zhou, Z Hu, L Han, W Zhao, T Wu, C Li… - European Journal of …, 2023 - Elsevier
Obesity, a global epidemic chronic metabolic disease, urgently demands novel therapies. As
an antimalarial drug, quinacrine has not been reported for its anti-obesity effect to our …

[HTML][HTML] The atypical antipsychotic risperidone targets hypothalamic melanocortin 4 receptors to cause weight gain

L Li, ES Yoo, X Li, SC Wyler, X Chen… - The Journal of …, 2021 - ncbi.nlm.nih.gov
Atypical antipsychotics such as risperidone cause drug-induced metabolic syndrome.
However, the underlying mechanisms remain largely unknown. Here, we report a new …

Myricetin improves metabolic outcomes but not cognitive deficit associated to metabolic syndrome in male mice

CFF Coelho, ILS Souza, VT Chagas, NLX Ribeiro… - Food & Function, 2021 - pubs.rsc.org
Myricetin is a flavonol highly prevalent in edible vegetables and fruits, with recognized
hypoglycemic and anti-obesity effects, besides great antioxidant capacity. Thus, this study …

The combined effect of metformin and mirabegron on diet‐induced obesity

XY Zhao, Y Liu, X Zhang, BC Zhao, G Burley… - MedComm, 2023 - Wiley Online Library
Anti‐obesity medications act by suppressing energy intake (EI), promoting energy
expenditure (EE), or both. Metformin (Met) and mirabegron (Mir) cause weight loss by …