Predictors of psychosis breakthrough during 24 months of long-acting antipsychotic maintenance treatment in first episode schizophrenia

R Emsley, L Asmal, JM Rubio, CU Correll… - Schizophrenia …, 2020 - Elsevier
Background Some patients develop breakthrough psychotic symptoms on antipsychotic
maintenance medication (BAMM), despite receiving therapeutic antipsychotic doses to …

[HTML][HTML] Psychosis breakthrough on antipsychotic maintenance medication (BAMM): what can we learn?

JM Rubio, JM Kane - npj Schizophrenia, 2017 - nature.com
Antipsychotic drugs are highly effective in preventing relapse among individuals with
schizophrenia, with a number needed to treat of 3. 1 Suboptimal adherence with …

Psychosis breakthrough on antipsychotic maintenance: results from a nationwide study

JM Rubio, H Taipale, CU Correll, A Tanskanen… - Psychological …, 2020 - cambridge.org
BackgroundThere is uncertainty about the incidence of breakthrough psychosis in treatment
adherent patients, and the role that factors, such as cumulative antipsychotic exposure, play …

Long-term effects of discontinuation from antipsychotic maintenance following first-episode schizophrenia and related disorders: a 10 year follow-up of a randomised …

CLM Hui, WG Honer, EHM Lee, WC Chang… - The Lancet …, 2018 - thelancet.com
Background The long-term consequences of discontinuing antipsychotic medication after
successful treatment of first-episode psychosis are not well studied. We assess the relation …

Psychosis relapse during treatment with long-acting injectable antipsychotics in individuals with schizophrenia-spectrum disorders: an individual participant data meta …

JM Rubio, G Schoretsanitis, M John, J Tiihonen… - The Lancet …, 2020 - thelancet.com
Background Most individuals with schizophrenia-spectrum disorders have relapses, which
increase the risk of morbidity and mortality. Because non-adherence to antipsychotic …

You say “schizophrenia” and I say “psychosis”: just tell me when I can come off this medication

RB Zipursky, G Odejayi, O Agid, G Remington - Schizophrenia Research, 2020 - Elsevier
Individuals experiencing a first episode of psychosis are likely to respond well to treatment
with antipsychotic medications. Of those treated for a first episode of schizophrenia, three out …

Antipsychotic medication and remission of psychotic symptoms 10 years after a first-episode psychosis

RS Wils, DR Gotfredsen, C Hjorthøj, SF Austin… - Schizophrenia …, 2017 - Elsevier
Background Several national guidelines recommend continuous use of antipsychotic
medication after a psychotic episode in order to minimize the risk of relapse. However some …

[HTML][HTML] Medication adherence and relapse in recent-onset psychosis

DG Robinson - American Journal of Psychiatry, 2011 - Am Psychiatric Assoc
Psychotic exacerbation is undesirable for any patient, but it is particularly important to
prevent psychotic exacerbations for recent-onset patients. Early relapse may disrupt …

Risk of symptom recurrence with medication discontinuation in first-episode psychosis: a systematic review

RB Zipursky, NM Menezes, DL Streiner - Schizophrenia Research, 2014 - Elsevier
The large majority of individuals with a first episode of schizophrenia will experience a
remission of symptoms within their first year of treatment. It is not clear how long treatment …

Rates and predictors of relapse following discontinuation of antipsychotic medication after a first episode of psychosis

M Bowtell, S Eaton, K Thien, M Bardell-Williams… - Schizophrenia …, 2018 - Elsevier
Background There is uncertainty about the required duration of long-term antipsychotic
maintenance medication after a first episode of psychosis. Robust predictors of relapse after …