Regular aerobic exercise, independently of weight loss, improves metabolic and anti-
inflammatory states, and can be regarded as beneficial in counteracting obesity-induced low …

Peroxisome proliferator‐activated receptors (PPARs) play a major role in metabolism and
inflammatory control. Exercise can modulate PPAR expression in skeletal muscle, adipose …

Moderate aerobic training may be therapeutic for chronic low-grade inflammatory diseases
due to the associated antiinflammatory response that is mediated by immune cells. The …

Background Exercise is a powerful tool for prevention and treatment of many conditions
related to the cardiovascular system and also chronic low‐grade inflammation. Peroxisome …

Anti-inflammatory regulatory T cells (Tregs) are the most metabolically flexible CD4+ T cells
by using both glycolysis and fatty acid oxidation (FAO) which allow them to migrate in …

Reduced physical activity rate in people's lifestyle is a global concern associated with the
prevalence of health disorders such as obesity and metabolic disturbance. Ample evidence …

Background Inflammation of adipose tissue (AT) has been recently accepted as a first step
towards obesity-mediated insulin resistance. We could previously show that mice fed with …

The nuclear transcriptional factor peroxisome proliferator activated receptor alpha (PPARα)
plays a role in regulating genes involved in lipid metabolism, adipogenesis and …

Increasing evidence points towards the existence of a bidirectional interconnection between
metabolic disease and neurodegenerative disorders, in which inflammation is linking both …

Anomalous immune/inflammatory responses in obesity take place along with alterations in
the neuroendocrine responses and dysregulation in the immune/stress feedback …