[HTML][HTML] Oxytocin signaling as a target to block social defeat-induced increases in drug abuse reward

C Ferrer-Pérez, MD Reguilón, J Miñarro… - International journal of …, 2021 - mdpi.com
There is huge scientific interest in the neuropeptide oxytocin (OXT) due to its putative
capacity to modulate a wide spectrum of physiological and cognitive processes including …

Oxytocin signaling in the treatment of drug addiction: Therapeutic opportunities and challenges

X Che, J Cai, Y Liu, T Xu, J Yang, C Wu - Pharmacology & therapeutics, 2021 - Elsevier
Drug addiction is one of the leading causes of mortality worldwide. Despite great advances
were achieved in understanding the neurobiology of drug addiction, the therapeutic options …

The role of oxytocin in alcohol and drug abuse

CE King, A Gano, HC Becker - Brain research, 2020 - Elsevier
The neuropeptide oxytocin (OXT) plays a key role in adaptive processes associated with
reward, tolerance, memory and stress responses. Through interactions with brain reward …

[HTML][HTML] Oxytocin and addiction: potential glutamatergic mechanisms

M Sundar, D Patel, Z Young, KC Leong - International journal of …, 2021 - mdpi.com
Recently, oxytocin (OXT) has been investigated for its potential therapeutic role in addiction.
OXT has been found to diminish various drug-seeking and drug-induced behaviors …

Oxytocin for the treatment of drug and alcohol use disorders

MR Lee, EM Weerts - Behavioural pharmacology, 2016 - journals.lww.com
There is growing interest in the use of oxytocin (OT) as a potential treatment for alcohol and
other substance-use disorders. OT is a neuropeptide that modulates adaptive processes …

Targeting the oxytocin system to treat addictive disorders: rationale and progress to date

MR Lee, MCH Rohn, G Tanda, L Leggio - CNS drugs, 2016 - Springer
The neuropeptide oxytocin plays a role in reward, stress, social affiliation, learning, and
memory processes. As such, there is increasing interest in oxytocin as a potential treatment …

[HTML][HTML] The role of oxytocin and vasopressin in drug-induced reward—implications for social and non-social factors

O Wronikowska-Denysiuk, W Mrozek, B Budzyńska - Biomolecules, 2023 - mdpi.com
Drug abuse is a worldwide problem that leads to negative physical, mental, and economic
consequences. Although pharmacological strategies for drug addiction management have …

[HTML][HTML] From autism to eating disorders and more: the role of oxytocin in neuropsychiatric disorders

A Romano, B Tempesta… - Frontiers in …, 2016 - frontiersin.org
Oxytocin (oxy) is a pituitary neuropeptide hormone synthesized from the paraventricular and
supraoptic nuclei within the hypothalamus. Like other neuropeptides, oxy can modulate a …

[HTML][HTML] Roles of oxytocin in stress responses, allostasis and resilience

Y Takayanagi, T Onaka - International journal of molecular sciences, 2021 - mdpi.com
Oxytocin has been revealed to work for anxiety suppression and anti-stress as well as for
psychosocial behavior and reproductive functions. Oxytocin neurons are activated by …

Assembling the puzzle: pathways of oxytocin signaling in the brain

V Grinevich, HS Knobloch-Bollmann, M Eliava… - Biological …, 2016 - Elsevier
Oxytocin (OT) is a neuropeptide, which can be seen to be one of the molecules of the
decade due to its profound prosocial effects in nonvertebrate and vertebrate species …