Evaluating And Exploiting The Substrate Selectivity Of Farnesyltransferase
G Schey - 2023 - conservancy.umn.edu
Protein prenylation is a post translational modification where an isoprenoid is attached to a
CaaX sequence at the c terminus of a protein. Ultimately, after this modification and …
CaaX sequence at the c terminus of a protein. Ultimately, after this modification and …
[HTML][HTML] Efficient farnesylation of an extended C-terminal C (x) 3X sequence motif expands the scope of the prenylated proteome
MJ Blanden, KF Suazo, ER Hildebrandt… - Journal of Biological …, 2018 - ASBMB
Protein prenylation is a post-translational modification that has been most commonly
associated with enabling protein trafficking to and interaction with cellular membranes. In …
associated with enabling protein trafficking to and interaction with cellular membranes. In …
Combinatorial modulation of protein prenylation
AJ Krzysiak, DS Rawat, SA Scott, JE Pais… - ACS chemical …, 2007 - ACS Publications
The cell has> 60 different farnesylated proteins. Many critically important signal transduction
proteins are post-translationally modified with attachment of a farnesyl isoprenoid catalyzed …
proteins are post-translationally modified with attachment of a farnesyl isoprenoid catalyzed …
Quantitative determination of cellular farnesyltransferase activity: towards defining the minimum substrate reactivity for biologically relevant protein farnesylation
SC Flynn, DE Lindgren, JL Hougland - ChemBioChem, 2014 - Wiley Online Library
Prenylation is a post‐translational modification wherein an isoprenoid group is attached to a
protein substrate by a protein prenyltransferase. Hundreds of peptide sequences are in vitro …
protein substrate by a protein prenyltransferase. Hundreds of peptide sequences are in vitro …
[PDF][PDF] MALDI/MS as a Tool to Rapidly Screen Peptide Libraries for Novel Substrates of Farnesyltransferase
G Schey, E Hildebrandt, S Novak, JL Hougland… - 2021 - sciforum.net
Protein farnesylation is a post-translational modification where a 15 carbon farnesyl
isoprenoid is appended to the C-terminal end of a protein by Farnesyltransferase (FTase). In …
isoprenoid is appended to the C-terminal end of a protein by Farnesyltransferase (FTase). In …
Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase
GL Schey, ER Hildebrandt, Y Wang, S Diwan… - International journal of …, 2024 - mdpi.com
Protein farnesylation is a post-translational modification where a 15-carbon farnesyl
isoprenoid is appended to the C-terminal end of a protein by farnesyltransferase (FTase) …
isoprenoid is appended to the C-terminal end of a protein by farnesyltransferase (FTase) …
Identification of novel peptide substrates for protein farnesyltransferase reveals two substrate classes with distinct sequence selectivities
JL Hougland, KA Hicks, HL Hartman, RA Kelly… - Journal of molecular …, 2010 - Elsevier
Prenylation is a posttranslational modification essential for the proper localization and
function of many proteins. Farnesylation, the attachment of a 15-carbon farnesyl group near …
function of many proteins. Farnesylation, the attachment of a 15-carbon farnesyl group near …
Expanding the Potential Prenylome: Prenylation of Shortened Target Substrates by Ftase and Development of Fret-Based System for Detecting Potentially “Shunted” …
S Ashok - 2020 - search.proquest.com
Protein prenylation is a posttranslational modification involving the attachment of a C15 or
C20 isoprenoid group to a cysteine residue near the C-terminus of the target substrate by …
C20 isoprenoid group to a cysteine residue near the C-terminus of the target substrate by …
Protein farnesyltransferase catalyzes unanticipated farnesylation and geranylgeranylation of shortened target sequences
S Ashok, ER Hildebrandt, CS Ruiz, DS Hardgrove… - Biochemistry, 2020 - ACS Publications
Protein prenylation is a posttranslational modification involving the attachment of a C15 or
C20 isoprenoid group to a cysteine residue near the C-terminus of the target substrate by …
C20 isoprenoid group to a cysteine residue near the C-terminus of the target substrate by …
[HTML][HTML] MALDI-MS analysis of peptide libraries expands the scope of substrates for farnesyltransferase
GL Schey, PH Buttery, ER Hildebrandt… - International journal of …, 2021 - mdpi.com
Protein farnesylation is a post-translational modification where a 15-carbon farnesyl
isoprenoid is appended to the C-terminal end of a protein by farnesyltransferase (FTase) …
isoprenoid is appended to the C-terminal end of a protein by farnesyltransferase (FTase) …