Thiophene containing trisubstituted methanes [TRSMs] as identified lead against Mycobacterium tuberculosis
Triarylmethanes (TRAMs) and thiophene containing trisubstituted methanes (TRSMs) have
been reported by us, having potential against Mycobacterium tuberculosis and …
been reported by us, having potential against Mycobacterium tuberculosis and …
Thiophene containing triarylmethanes as antitubercular agents
MK Parai, G Panda, V Chaturvedi, YK Manju… - Bioorganic & Medicinal …, 2008 - Elsevier
A new series of thiophene containing triarylmethane derivatives were synthesized from the
Friedel–Crafts alkylation of diarylcarbinols followed by incorporation of amino alkyl chains …
Friedel–Crafts alkylation of diarylcarbinols followed by incorporation of amino alkyl chains …
Dibenzofuran, dibenzothiophene and N-methyl carbazole tethered 2-aminothiazoles and their cinnamamides as potent inhibitors of Mycobacterium tuberculosis
G Surineni, SK Marvadi, P Yogeeswari, D Sriram… - Bioorganic & Medicinal …, 2018 - Elsevier
Herein described the design, synthesis and antitubercular evaluation of novel series of
dibenzofuran, dibenzothiophene and N-methyl carbazole tethered 2-aminothiazoles and …
dibenzofuran, dibenzothiophene and N-methyl carbazole tethered 2-aminothiazoles and …
Structure–activity relationship of 2-aminodibenzothiophene pharmacophore and the discovery of aminobenzothiophenes as potent inhibitors of Mycobacterium …
Tuberculosis (TB) is one of the deadliest infectious diseases worldwide and its current
treatments have been complicated with the emergence of multi-drug resistant (MDR-TB) and …
treatments have been complicated with the emergence of multi-drug resistant (MDR-TB) and …
Synthesis and evaluation of new 2-aminothiophenes against Mycobacterium tuberculosis
S Thanna, SE Knudson, A Grzegorzewicz… - Organic & …, 2016 - pubs.rsc.org
Tuberculosis (TB) and its drug resistant forms kills more people than any other infectious
disease. This fact emphasizes the need to identify new drugs to treat TB. 2-Aminothiophenes …
disease. This fact emphasizes the need to identify new drugs to treat TB. 2-Aminothiophenes …
Anti-tubercular activities of 5, 6, 7, 8-tetrahydrobenzo [4, 5] thieno [2, 3-d] pyrimidin-4-amine analogues endowed with high activity toward non-replicative …
Thirty three derivatives of 2-substituted 5, 6, 7, 8-tetrahydrobenzo [4, 5] thieno [2, 3-d]
pyrimidin-4-amine analogues were synthesized by molecular modification of a reported …
pyrimidin-4-amine analogues were synthesized by molecular modification of a reported …
Synthesis and biological evaluation of N-(aryl)-2-thiophen-2-ylacetamides series as a new class of antitubercular agents
MCS Lourenço, FR Vicente, MGM de Oliveira… - Bioorganic & medicinal …, 2007 - Elsevier
The present article describes a series of 21 N-(aryl)-2-thiophen-2-ylacetamides, which were
synthesized and evaluated for their in vitro antibacterial activity against Mycobacterium …
synthesized and evaluated for their in vitro antibacterial activity against Mycobacterium …
Identification of thiophene-benzenesulfonamide derivatives for the treatment of multidrug-resistant tuberculosis
R Qin, P Wang, B Wang, L Fu, SM Batt… - European Journal of …, 2022 - Elsevier
A series of thiophene-benzenesulfonamide derivatives was designed and synthesized by
exploring the structure-activity relationship of lead compounds 2, 3-disubstituted thiophenes …
exploring the structure-activity relationship of lead compounds 2, 3-disubstituted thiophenes …
Synthesis and Antitubercular Activity of New Benzo[b]thiophenes
PS Mahajan, MD Nikam, LU Nawale… - ACS Medicinal …, 2016 - ACS Publications
In vitro and ex vivo efficacies of four series of benzo [b] thiophene-2-carboxylic acid
derivatives were studied against Mycobacterium tuberculosis H37Ra (MTB). Benzo [b] …
derivatives were studied against Mycobacterium tuberculosis H37Ra (MTB). Benzo [b] …
Novel thiourea derivatives against Mycobacterium tuberculosis: synthesis, characterization and molecular docking studies
Abstract N-((2-chloropyridin-3-yl) carbamothioyl) thiophene-2-carboxamide (HL1), N-((6-
methylpyridin-2-yl) carbamothioyl) thiophene-2-carboxamide (HL2), N-(allylcarbamothioyl) …
methylpyridin-2-yl) carbamothioyl) thiophene-2-carboxamide (HL2), N-(allylcarbamothioyl) …