Effects and mechanisms of Danshen-Shanzha herb-pair for atherosclerosis treatment using network pharmacology and experimental pharmacology

J Zhang, R Liang, L Wang, B Yang - Journal of ethnopharmacology, 2019 - Elsevier
Ethnopharmacological relevance The danshen (the root of Salvia miltiorrhiza Bge.)-shanzha
(the fruit of Crataegus pinnatifida Bge. var. major NE Br.)(DS) herb combination is a …

The roots of Salvia miltiorrhiza (Danshen) and Pueraria lobata (Gegen) inhibit atherogenic events: a study of the combination effects of the 2-herb formula

DWS Cheung, CM Koon, CF Ng, PC Leung… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: The roots of Salvia miltiorrhiza (Danshen) and
Pueraria lobata (Gegen) are principle herbs of Chinese herbal formulae which have long …

Therapeutic effects of water soluble danshen extracts on atherosclerosis

YH Cho, CR Ku, ZY Hong, JH Heo… - Evidence‐based …, 2013 - Wiley Online Library
Danshen is a traditional Chinese medicine with many beneficial effects on cardiovascular
diseases. The aim of this study was to evaluate the mechanisms responsible for the …

Anti-Inflammatory Effects of Danshen on Human Vascular Endothelial Cells in Culture

C Stumpf, Q Fan, C Hintermann, D Raaz… - The American journal …, 2013 - World Scientific
Inflammation plays a crucial role in the pathophysiology of atherosclerosis. Besides
cytokines, chemokines and cell adhesion molecules, CD40 and P-selectin play important …

Systems pharmacological study based on UHPLC-Q-Orbitrap-HRMS, network pharmacology and experimental validation to explore the potential mechanisms of …

Y Bi, X Han, Y Lai, Y Fu, K Li, W Zhang, Q Wang… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Atherosclerosis (AS) plays an important role in the
pathogenesis of cardiovascular and cerebrovascular diseases. Danggui-Shaoyao-San …

Synergistic effects of danshen (salvia miltiorrhiza radix et rhizoma) and sanqi (notoginseng radix et rhizoma) combination in inhibiting inflammation mediators in …

X Zhou, V Razmovski-Naumovski… - BioMed Research …, 2016 - Wiley Online Library
Aims. This study aims to investigate the possible synergistic interactions of the Danshen‐
Sanqi combination on vascular disease via their anti‐inflammatory activities. Methods. Nine …

Combination of Danshen and ligustrazine has dual anti-inflammatory effect on macrophages and endothelial cells

T Ye, Y Li, D Xiong, S Gong, L Zhang, B Li, J Pan… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Salvia Miltiorrhiza Radix et Rhizoma (Danshen)
and Chuanxiong Rhizoma (Chuanxiong) are both traditional Chinese medicines with …

Chinese herbs Danshen and Gegen modulate key early atherogenic events in vitro

DP Sieveking, KS Woo, KP Fung, P Lundman… - International journal of …, 2005 - Elsevier
Danshen (Salvia miltiorrhiza) and Gegen (Radix puerariae) are two herbs used in traditional
Chinese medicine, most commonly for their putative cardioprotective and anti …

Study of the protective mechanisms of Compound Danshen Tablet (Fufang Danshen Pian) against myocardial ischemia/reperfusion injury via the Akt-eNOS signaling …

Q Ren-an, L Juan, L Chuyuan, F Wenjuan… - Journal of …, 2014 - Elsevier
Abstract Ethnopharmacological relevance Compound Danshen Tablet (CDT), an herbal
preparation consisting of Salvia miltiorrhiza (Radix and rhizome of Salvia miltiorrhiza Bge.) …

Danshen (Salvia miltiorrhiza Bunge): a prospective healing sage for cardiovascular diseases

W Chen, G Chen - Current Pharmaceutical Design, 2017 - ingentaconnect.com
Danshen (Salvia miltiorrhiza Bunge) is a valued herbal plant in the Traditional Chinese
Medicine. The dried root of this plant (Radix Salvia miltiorrhiza), either alone or in …