Epigenetic mechanisms of DNA methylation in the transgenerational effect of ethylhexyl salicylate on zebrafish

R Zhou, G Lu, Z Yan, R Jiang, Y Sun, P Zhang - Chemosphere, 2022 - Elsevier
In this study, a 120-day whole-life cycle exposure and oviposition experiment on zebrafish
with maternal and paternal mixed mating strategy was conducted to investigate the …

Global DNA methylation in gonads of adult zebrafish Danio rerio under bisphenol A exposure

Y Liu, Y Zhang, S Tao, Y Guan, T Zhang… - … and environmental safety, 2016 - Elsevier
Altered DNA methylation is pervasively associated with changes in gene expression and
signal transduction after exposure to a wide range of endocrine disrupting chemicals. As a …

2, 4-Dichlorophenol induced feminization of zebrafish by down-regulating male-related genes through DNA methylation

C Yuan, C Zhang, Y Qi, D Li, Y Hu, D Huang - … and Environmental Safety, 2020 - Elsevier
Dichlorophenol (2, 4-DCP) is ubiquitous in aquatic environment and has potential
estrogenic effect on fish. However, the effect of 2, 4-DCP on sex differentiation of zebrafish …

Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono (2 …

JH Kamstra, LB Sales, P Aleström, J Legler - Epigenetics & chromatin, 2017 - Springer
Background Exposure to environmental stressors during development may lead to latent
and transgenerational adverse health effects. To understand the role of DNA methylation in …

Impacts of TCDD and MeHg on DNA methylation in zebrafish (Danio rerio) across two generations

PA Olsvik, TD Williams, H Tung, L Mirbahai… - … and Physiology Part C …, 2014 - Elsevier
This study aimed to investigate whether dioxin (TCDD) and methylmercury (MeHg) pose a
threat to offspring of fish exposed to elevated concentrations of these chemicals via …

Toxicological effects of atenolol and venlafaxine on zebrafish tissues: Bioaccumulation, DNA hypomethylation, and molecular mechanism

W Lin, Z Huang, S Ping, S Zhang, X Wen, Y He… - Environmental …, 2022 - Elsevier
The beta-blocker atenolol (ATE), and the selective serotonin and norepinephrine reuptake
inhibitor, venlafaxine (VEN) are frequently detected in municipal wastewater effluents, but …

Benzo [a] pyrene decreases global and gene specific DNA methylation during zebrafish development

X Fang, C Thornton, BE Scheffler, KL Willett - Environmental toxicology and …, 2013 - Elsevier
DNA methylation is important for gene regulation and is vulnerable to early-life exposure to
environmental contaminants. We found that direct waterborne benzo [a] pyrene (BaP) …

2, 4-Dichlorophenol induces global DNA hypermethylation through the increase of S-adenosylmethionine and the upregulation of DNMTs mRNA in the liver of …

X Zhang, H Li, Q Qiu, Y Qi, D Huang, Y Zhang - … and Physiology Part C …, 2014 - Elsevier
Altered DNA methylation is associated with changes in gene expression, signal transduction
and stress response after exposure to a wide range of exogenous compounds, and …

Zebrafish as a model to study the role of DNA methylation in environmental toxicology

JH Kamstra, P Aleström, JM Kooter, J Legler - Environmental Science and …, 2015 - Springer
Environmental epigenetics is a rapidly growing field which studies the effects of
environmental factors such as nutrition, stress, and exposure to compounds on epigenetic …

Development of a screening system for the detection of chemically induced DNA methylation alterations in a zebrafish liver cell line

E Farmen, MT Hultman, MA d'Auriac… - Journal of Toxicology …, 2014 - Taylor & Francis
Early molecular events with correlation to disease, such as aberrant DNA methylation,
emphasize the importance of DNA methylation as a potential environmental biomarker …