Bitter taste receptor mTas2r105 is expressed in small intestinal villus and crypts
F Gu, X Liu, J Liang, J Chen, F Chen, F Li - Biochemical and biophysical …, 2015 - Elsevier
The small intestine is the most important digestion and absorption organ in the body. Taste
receptors and taste signal transduction cascades were detected in a variety of non-lingual …
receptors and taste signal transduction cascades were detected in a variety of non-lingual …
Oligomerization of TAS2R bitter taste receptors
A family of 25 G protein–coupled receptors, TAS2Rs, mediates bitter taste in humans. Many
of the members of this family are coexpressed in a subpopulation of taste receptor cells on …
of the members of this family are coexpressed in a subpopulation of taste receptor cells on …
Do polymorphisms in chemosensory genes matter for human ingestive behavior?
In the last decade, basic research in chemoreceptor genetics and neurobiology has
revolutionized our understanding of individual differences in chemosensation. From an …
revolutionized our understanding of individual differences in chemosensation. From an …
[HTML][HTML] Bitter taste sensitivity is determined by TAS2R38 haplotype, associated with saturated fat intake and is lower in overweight and obese compared to normal …
L Pilic, CAM Graham, N Hares, M Brown, J Kean… - Current Developments …, 2020 - Elsevier
Objectives Taste perception (sensitivity) may be determined by genetic variations in taste
receptors and it affects food intake. Lower fat taste sensitivity is associated with higher …
receptors and it affects food intake. Lower fat taste sensitivity is associated with higher …
Genetic and environmental determinants of bitter perception and sweet preferences
Objective. Flavor is the primary dimension by which young children determine food
acceptance. However, children are not merely miniature adults because sensory systems …
acceptance. However, children are not merely miniature adults because sensory systems …
Analysis of the expression of human bitter taste receptors in extraoral tissues
A Jaggupilli, N Singh, J Upadhyaya… - Molecular and cellular …, 2017 - Springer
The 25 bitter taste receptors (T2Rs) in humans perform a chemosensory function. However,
very little is known about the level of expression of these receptors in different tissues. In this …
very little is known about the level of expression of these receptors in different tissues. In this …
Association of TAS2R38 variants with sweet food intake in children aged 1–6 years
I Pawellek, V Grote, P Rzehak, A Xhonneux, E Verduci… - Appetite, 2016 - Elsevier
We aimed at studying whether genetic variants of the TAS2R38 gene are associated with
energy intake from sweet tasting foods, total energy and macronutrient intake and body …
energy intake from sweet tasting foods, total energy and macronutrient intake and body …
Genetic variations of the bitter taste receptor TAS2R38 are associated with obesity and impact on single immune traits
FJ Ortega, Z Agüera, M Sabater… - Molecular Nutrition & …, 2016 - Wiley Online Library
Scope Changes in genetic variations affecting the taste receptor, type 2, member 38
(TAS2R38) may identify the interacting mechanism leading to obesity and potential …
(TAS2R38) may identify the interacting mechanism leading to obesity and potential …
Selection on the human bitter taste gene, TAS2R16, in Eurasian populations
H Li, AJ Pakstis, JR Kidd, KK Kidd - Human Biology, 2011 - BioOne
Bitter taste is one of the most important senses alerting humans to noxious foods. In gatherer
communities, sensitivity to bitterness is presumably advantageous because of various …
communities, sensitivity to bitterness is presumably advantageous because of various …
Amino acids and peptides activate at least five members of the human bitter taste receptor family
S Kohl, M Behrens, A Dunkel, T Hofmann… - Journal of agricultural …, 2013 - ACS Publications
Amino acids and peptides represent important flavor molecules eliciting various taste
sensations. Here, we present a comprehensive assessment of the interaction of various …
sensations. Here, we present a comprehensive assessment of the interaction of various …