Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder
characterized by impairments in synaptic plasticity and cognitive performance. Cognitive …

Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder of
middle-aged to old individuals. The pathophysiological process of AD is believed to begin …

Besides the presence of amyloid beta (Aβ) plaques and neurofibrillary tangles,
neurogenesis and synaptic plasticity are markedly impaired in Alzheimer's disease (AD) …

Background The use of neurotrophic factors to treat Alzheimer's disease (AD) is hindered by
their blood–brain barrier impermeability, short half-life, and severe side effects. Peptide 021 …

To date, neither any effective treatment nor prevention of Alzheimer's disease (AD), a major
dementia causing disorder, are available. Herein, we investigated the secondary prevention …

In addition to the occurrence of numerous neurofibrillary tangles and Aβ plaques,
neurogenesis and neuronal plasticity are markedly altered in Alzheimer disease (AD) …

Alzheimer's disease (AD) is the single major cause of dementia in middle-to old-age
individuals, and, as of yet, no disease-modifying therapeutic drug is available for its …

Alzheimer's disease (AD) is multifactorial and, to date, no single cause of the sporadic form
of this disease, which accounts for over 99% of the cases, has been established. In AD …

Aging is characterized by a progressive decline of cognitive performance, which has been
partially attributed to structural and functional alterations of hippocampus. Importantly, aging …

Reduced expression of brain-derived neurotrophic factor (BDNF) has a crucial role in the
pathogenesis of Alzheimer's disease (AD), which is characterized with the formation of …