CRISPR/Cas9-mediated SlAN2 mutants reveal various regulatory models of anthocyanin biosynthesis in tomato plant

J Zhi, X Liu, D Li, Y Huang, S Yan, B Cao, Z Qiu - Plant cell reports, 2020 - Springer
Key message Combining phenotype and gene expression analysis of the CRISPR/Cas9-
induced SlAN2 mutants, we revealed that SlAN2 specifically regulated anthocyanin …

Development and application of CRISPR/Cas9 to improve anthocyanin pigmentation in plants: Opportunities and perspectives

E Mackon, GCJDE Mackon, Y Guo, Y Ma, Y Yao, P Liu - Plant Science, 2023 - Elsevier
Since its discovery in 2012, the novel technology of clustered regularly interspaced short
palindromic repeats (CRISPR) and CRISPR-associated protein 9 (Cas9) has greatly …

Anthocyanin Fruit encodes an R2R3‐MYB transcription factor, SlAN2‐like, activating the transcription of SlMYBATV to fine‐tune anthocyanin content in tomato fruit

S Yan, N Chen, Z Huang, D Li, J Zhi, B Yu… - New …, 2020 - Wiley Online Library
Anthocyanin fruit (Aft) and atroviolacea (atv) were characterized in wild tomato and can
enhance anthocyanin content in tomato fruit. However, the gene underlying the Aft locus and …

A dual-function transcription factor, SlJAF13, promotes anthocyanin biosynthesis in tomato

Y Chen, P Kim, L Kong, X Wang, W Tan… - Journal of …, 2022 - academic.oup.com
Unlike modern tomato (Solanum lycopersicum) cultivars, cv. LA1996 harbors the dominant
Aft allele, which is associated with anthocyanin synthesis in tomato fruit peel. However, the …

Identification of candidate HY5-dependent and-independent regulators of anthocyanin biosynthesis in tomato

Z Qiu, H Wang, D Li, B Yu, Q Hui, S Yan… - Plant and Cell …, 2019 - academic.oup.com
High quantities of anthocyanins in plants confer potential protective benefits against biotic
and abiotic stressors. Studies have shown that the bZIP transcription factor HY5 plays a key …

[HTML][HTML] A transcriptional network promotes anthocyanin biosynthesis in tomato flesh

C Sun, L Deng, M Du, J Zhao, Q Chen, T Huang… - Molecular Plant, 2020 - cell.com
Dietary anthocyanins are important health-promoting antioxidants that make a major
contribution to the quality of fruits. It is intriguing that most tomato cultivars do not produce …

[HTML][HTML] Tomato R2R3-MYB proteins SlANT1 and SlAN2: same protein activity, different roles

C Kiferle, E Fantini, L Bassolino, G Povero, C Spelt… - PLoS …, 2015 - journals.plos.org
Anthocyanins are water-soluble polyphenolic compounds with a high nutraceutical value.
Despite the fact that cultivated tomato varieties do not accumulate anthocyanins in the fruit …

[HTML][HTML] Molecular characterization of an anthocyanin-related glutathione S-transferase gene in Japanese gentian with the CRISPR/Cas9 system

K Tasaki, M Yoshida, M Nakajima, A Higuchi… - BMC Plant …, 2020 - Springer
Background The blue pigmentation of Japanese gentian flowers is due to a polyacylated
anthocyanin, gentiodelphin, and all associated biosynthesis genes and several regulatory …

ANTHOCYANIN1 from Solanum chilense is more efficient in accumulating anthocyanin metabolites than its Solanum lycopersicum counterpart in …

G Schreiber, M Reuveni, D Evenor… - Theoretical and Applied …, 2012 - Springer
Anthocyanins are flavonoid metabolites contributing attractive colors and antioxidant
qualities to the human diet. Accordingly, there is a growing interest in developing crops …

[HTML][HTML] Alternative splicing in the anthocyanin fruit gene encoding an R2R3 MYB transcription factor affects anthocyanin biosynthesis in tomato fruits

S Colanero, A Tagliani, P Perata, S Gonzali - Plant communications, 2020 - cell.com
Tomato (Solanum lycopersicum) fruits are typically red at ripening, with high levels of
carotenoids and a low content in flavonoids. Considerable work has been done to enrich the …