Low-protein and methionine, high-starch diets increase energy intake and expenditure, increase FGF21, decrease IGF-1, and have little effect on adiposity in mice

C Chaumontet, D Azzout-Marniche… - American Journal …, 2019 - journals.physiology.org
Low-protein diets most often induce increased energy intake in an attempt to increase
protein intake to meet protein needs with a risk of accumulation as fat of the excess energy …

Hepatic, adipocyte, enteric and pancreatic hormones: response to dietary macronutrient composition and relationship with metabolism

BM Hron, CB Ebbeling, HA Feldman, DS Ludwig - Nutrition & metabolism, 2017 - Springer
Background We sought to characterize the effects of dietary macronutrient composition on
various hormones implicated in the regulation of insulin sensitivity (IS) and energy …

Low protein diets produce divergent effects on energy balance

A Pezeshki, RC Zapata, A Singh, NJ Yee… - Scientific reports, 2016 - nature.com
Diets deficient in protein often increase food consumption, body weight and fat mass;
however, the underlying mechanisms remain poorly understood. We compared the effects of …

[HTML][HTML] Chronic high-sucrose diet increases fibroblast growth factor 21 production and energy expenditure in mice

R Maekawa, Y Seino, H Ogata, M Murase, A Iida… - The Journal of nutritional …, 2017 - Elsevier
Excess carbohydrate intake causes obesity in humans. On the other hand, acute
administration of fructose, glucose or sucrose in experimental animals has been shown to …

A high-protein diet reduces weight gain, decreases food intake, decreases liver fat deposition, and improves markers of muscle metabolism in obese Zucker rats

WW French, S Dridi, SA Shouse, H Wu, A Hawley… - Nutrients, 2017 - mdpi.com
A primary factor in controlling and preventing obesity is through dietary manipulation. Diets
higher in protein have been shown to improve body composition and metabolic health …

Hypocaloric high-protein diet improves fatty liver and hypertriglyceridemia in sucrose-fed obese rats via two pathways

T Uebanso, Y Taketani, M Fukaya… - American Journal …, 2009 - journals.physiology.org
The mechanism by which replacement of some dietary carbohydrates with protein during
weight loss favors lipid metabolism remains obscure. In this study, we investigated the effect …

Protein source in a high‐protein diet modulates reductions in insulin resistance and hepatic steatosis in fa/fa Zucker rats

JL Wojcik, JG Devassy, Y Wu, P Zahradka, CG Taylor… - …, 2016 - Wiley Online Library
Objective High‐protein diets are being promoted to reduce insulin resistance and hepatic
steatosis in metabolic syndrome. Therefore, the effect of protein source in high‐protein diets …

Effects of long-term soluble vs. insoluble dietary fiber intake on high-fat diet-induced obesity in C57BL/6J mice

F Isken, S Klaus, M Osterhoff, AFH Pfeiffer… - The Journal of nutritional …, 2010 - Elsevier
Although most of the proposed beneficial effects of fiber consumption have been attributed
to viscous and gel-forming properties of soluble fiber, it is mainly insoluble cereal fiber and …

[HTML][HTML] Mice Regulate Dietary Amino Acid Balance and Energy Intake by Selecting between Complementary Protein Sources

K Zaman, H Mun, SM Solon-Biet, AM Senior… - The Journal of …, 2024 - Elsevier
Background A balanced intake of protein and constituent amino acids (AAs) requires
adjustments to total food intake (protein leverage [PL]) and food selection to balance deficits …

Intestinal serine protease inhibition increases FGF21 and improves metabolism in obese mice

K Albarazanji, M Jennis… - American Journal …, 2019 - journals.physiology.org
Trypsin is the major serine protease responsible for intestinal protein digestion. An inhibitor,
camostat (CS), reduced weight gain, hyperglycemia, and dyslipidemia in obese rats; …