The preimplantation period of embryonic development can be a key window for
programming of postnatal development because extensive epigenetic remodeling occurs …

Choline is a vital micronutrient. In this study, we aimed to confirm, and expand on previous
findings, how choline impacts embryos from the first 7 days of development to affect …

Choline is a precursor of acetylcholine, phosphatidylcholine, and the methyl-donor betaine.
Reports indicate that supplementation with rumen-protected choline improves postpartum …

There is species divergence in control of DNA methylation during preimplantation
development. The exact pattern of methylation in the bovine embryo has not been …

During early mammalian embryogenesis, there is a wave of DNA demethylation
postfertilization and de novo methylation around implantation. The paternal genome …

During gestation there is a high demand for the essential nutrient choline. Adult rats
supplemented with choline during embryonic days (E) 11-17 have improved memory …

The methylation pathway, which consists of two metabolic cycles of nutrients, ie, the
methionine and folate cycles, generates S‐adenosylmethionine, the methyl donor for the …

Purpose Maternal diet during pregnancy impacts foetal growth and development. In
particular, dietary levels of methylating micronutrients (methionine, folate, choline, vitamins …

Purpose We tested whether in vitro production (IVP) causes changes in DNA methylation in
fetal liver and skeletal muscle and if exposure of cultured embryos to colony-stimulating …

Supplementation of micronutrients involved in DNA methylation, particularly during
pregnancy, is recommended because of its impacts on human health, but further evidence is …