Angiogenesis is a common feature of many physiological processes and pathological
conditions. RGD-containing peptides can strongly bind to integrin αvβ3 expressed on …

Imaging techniques targeting tumor angiogenesis have been investigated for past decade.
Of these, the radiolabeled Arg-Gly-Asp (RGD) peptide has been focused because it has high …

Purpose Our goal was to demonstrate that suitably derivatized monomeric RGD peptide-
based PET tracers, targeting integrin α v β 3, may offer advantages in image contrast, time …

Molecular imaging for non-invasive assessment of angiogenesisis is of great interest for
clinicians because of the wide-spread application of anti-angiogenic cancer therapeutics …

Purpose Non-invasive PET imaging with radiolabeled RGD peptides for α v β 3 integrin
targeting has become an important tool for tumor diagnosis and treatment monitoring in both …

The cell adhesion molecule integrin αvβ3 is an important player in the process of
angiogenesis. In the last decades, a series of radiolabeled Arg-Gly-Asp (RGD) peptides …

Glycosylation frequently improves the biokinetics and clearance properties of
macromolecules in vivo and could therefore be used for the design of radiopharmaceuticals …

Abstract Purpose Various radiolabeled Arg-Gly-Asp (RGD) peptides have been previously
investigated for tumor integrin α v β 3 imaging. To further develop RGD radiotracers with …

Integrin αvβ3 plays a critical role in tumor-induced angiogenesis and metastasis and has
become a promising diagnostic indicator and therapeutic target for various solid tumors …

Angiogenesis imaging is important for diagnostic and therapeutic treatment of various
malignant and nonmalignant diseases. The Arg-Gly-Asp (RGD) sequence has been known …