Causes and consequences of sperm mitochondrial dysfunction

D Durairajanayagam, D Singh, A Agarwal… - Andrologia, 2021 - Wiley Online Library
Mitochondria have multiple functions, including synthesis of adenine triphosphate,
production of reactive oxygen species, calcium signalling, thermogenesis and apoptosis …

[HTML][HTML] Mitochondria functionality and sperm quality

A Amaral, B Lourenço, M Marques… - …, 2013 - rep.bioscientifica.com
Although mitochondria are best known for being the eukaryotic cell powerhouses, these
organelles participate in various cellular functions besides ATP production, such as calcium …

Mitochondria, spermatogenesis, and male infertility–An update

S Vertika, KK Singh, S Rajender - Mitochondrion, 2020 - Elsevier
The incorporation of mitochondria in the eukaryotic cell is one of the most enigmatic events
in the course of evolution. This important organelle was thought to be only the powerhouse …

Mitochondria: their role in spermatozoa and in male infertility

M Boguenet, PE Bouet, A Spiers… - Human …, 2021 - academic.oup.com
BACKGROUND The best-known role of spermatozoa is to fertilize the oocyte and to transmit
the paternal genome to offspring. These highly specialized cells have a unique structure …

The sperm mitochondrion: Organelle of many functions

CR Moraes, S Meyers - Animal reproduction science, 2018 - Elsevier
This review summarizes current research in sperm mitochondrial function with specific
emphasis on mitochondrial metabolism, reactive oxygen species production and …

[HTML][HTML] Evaluation of sperm mitochondrial function: a key organelle for sperm motility

F Barbagallo, S La Vignera, R Cannarella… - Journal of Clinical …, 2020 - mdpi.com
Introduction: The role of nutraceuticals in the treatment of male infertility, especially in the
“idiopathic form”, remains the subject of significant debate. Many antioxidants improve …

[HTML][HTML] Not all sperm are equal: functional mitochondria characterize a subpopulation of human sperm with better fertilization potential

AP Sousa, A Amaral, M Baptista, R Tavares… - PloS one, 2011 - journals.plos.org
Human sperm samples are very heterogeneous and include a low amount of truly functional
gametes. Distinct strategies have been developed to characterize and isolate this specific …

[HTML][HTML] Mitochondrial functionality in male fertility: from spermatogenesis to fertilization

YJ Park, MG Pang - Antioxidants, 2021 - mdpi.com
Mitochondria are structurally and functionally distinct organelles that produce adenosine
triphosphate (ATP) through oxidative phosphorylation (OXPHOS), to provide energy to …

[HTML][HTML] Mitochondria quality control and male fertility

J Costa, PC Braga, I Rebelo, PF Oliveira, MG Alves - Biology, 2023 - mdpi.com
Simple Summary Mitochondria play a crucial role in numerous cellular processes, including
energy production, apoptosis, and calcium homeostasis. In the male reproductive system …

Mitochondria in mammalian sperm physiology and pathology: a review

FJ Pena, H Rodríguez Martínez… - … in Domestic Animals, 2009 - Wiley Online Library
Contents While, for a long time, the role of mitochondria in sperm physiology and pathology
has been largely ignored, recent research points out the mitochondria as a major organelle …