[HTML][HTML] Cerebral small vessel disease in sporadic and familial Alzheimer disease
RN Kalaria, D Sepulveda-Falla - The American journal of pathology, 2021 - Elsevier
Alzheimer disease (AD) is the most common cause of dementia. Biological definitions of AD
are limited to the cerebral burden of amyloid β plaques, neurofibrillary pathology, and …
are limited to the cerebral burden of amyloid β plaques, neurofibrillary pathology, and …
Small vessel disease and Alzheimer's dementia: pathological considerations
RN Kalaria - Cerebrovascular Diseases, 2002 - karger.com
Current evidence suggests that the neuropathology of Alzheimer type of dementia
comprises more than amyloid plaques and neurofibrillary tangles. At least a third of …
comprises more than amyloid plaques and neurofibrillary tangles. At least a third of …
[HTML][HTML] The overlap between vascular disease and Alzheimer's disease-lessons from pathology
J Attems, KA Jellinger - BMC medicine, 2014 - Springer
Recent epidemiological and clinico-pathological data indicate considerable overlap
between cerebrovascular disease (CVD) and Alzheimer's disease (AD) and suggest …
between cerebrovascular disease (CVD) and Alzheimer's disease (AD) and suggest …
Vascular dementia: clinicopathologic and genetic considerations
HV Vinters, C Zarow, E Borys… - Neuropathology and …, 2018 - Wiley Online Library
The incidence and severity of cerebrovascular disease (CVD) increase with advancing age,
as does the risk of developing Alzheimer's disease (AD). Not surprisingly, heterogeneous …
as does the risk of developing Alzheimer's disease (AD). Not surprisingly, heterogeneous …
Small vessel disease, but neither amyloid load nor metabolic deficit, is dependent on age at onset in Alzheimer's disease
M Ortner, A Kurz, P Alexopoulos, F Auer… - Biological …, 2015 - Elsevier
Background There is controversy concerning whether Alzheimer's disease (AD) with early
onset is distinct from AD with late onset with regard to amyloid pathology and neuronal …
onset is distinct from AD with late onset with regard to amyloid pathology and neuronal …
[HTML][HTML] Modifiable and non-modifiable risk factors of dementia on midlife cerebral small vessel disease in cognitively healthy middle-aged adults: the PREVENT …
A Low, MA Prats-Sedano, E McKiernan… - Alzheimer's research & …, 2022 - Springer
Background Considerable overlap exists between the risk factors of dementia and cerebral
small vessel disease (SVD). However, studies remain limited to older cohorts wherein …
small vessel disease (SVD). However, studies remain limited to older cohorts wherein …
The contribution of small vessel disease to subtypes of Alzheimer's disease: a study on cerebrospinal fluid and imaging biomarkers
We investigated whether subtypes of Alzheimer's disease (AD), that is, typical, limbic-
predominant, hippocampal-sparing, and minimal atrophy AD, had a specific signature of …
predominant, hippocampal-sparing, and minimal atrophy AD, had a specific signature of …
[HTML][HTML] Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
Contemplating Alzheimer's disease and the contribution of white matter hyperintensities
AM Brickman - Current neurology and neuroscience reports, 2013 - Springer
As the older adult segment of the population increases, Alzheimer's disease (AD) has
emerged as a significant public health epidemic. Over the past 3 decades, advances in the …
emerged as a significant public health epidemic. Over the past 3 decades, advances in the …
Cerebral small vessel disease and the risk of Alzheimer's disease: a systematic review
Background Cerebral small vessel disease (CSVD) comprises a variety of disorders
affecting small arteries and microvessels of the brain, manifesting as white matter …
affecting small arteries and microvessels of the brain, manifesting as white matter …