Alzheimer disease (AD) is the most common cause of dementia. Biological definitions of AD
are limited to the cerebral burden of amyloid β plaques, neurofibrillary pathology, and …

Current evidence suggests that the neuropathology of Alzheimer type of dementia
comprises more than amyloid plaques and neurofibrillary tangles. At least a third of …

Recent epidemiological and clinico-pathological data indicate considerable overlap
between cerebrovascular disease (CVD) and Alzheimer's disease (AD) and suggest …

The incidence and severity of cerebrovascular disease (CVD) increase with advancing age,
as does the risk of developing Alzheimer's disease (AD). Not surprisingly, heterogeneous …

Background There is controversy concerning whether Alzheimer's disease (AD) with early
onset is distinct from AD with late onset with regard to amyloid pathology and neuronal …

Background Considerable overlap exists between the risk factors of dementia and cerebral
small vessel disease (SVD). However, studies remain limited to older cohorts wherein …

We investigated whether subtypes of Alzheimer's disease (AD), that is, typical, limbic-
predominant, hippocampal-sparing, and minimal atrophy AD, had a specific signature of …

Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …

As the older adult segment of the population increases, Alzheimer's disease (AD) has
emerged as a significant public health epidemic. Over the past 3 decades, advances in the …

Background Cerebral small vessel disease (CSVD) comprises a variety of disorders
affecting small arteries and microvessels of the brain, manifesting as white matter …