OBJECTIVES: Population ageing and the increasing burden of chronic conditions challenge
traditional metrics of assessing the efficacy of health care interventions and as a …

Objective To support decision making on how to best redesign chronic care by studying the
heterogeneity in effectiveness across chronic care management evaluations for heart failure …

Chronic heart failure (CHF) is a multi-dimensional and complex syndrome. Outcome
measures are important for determining both the efficacy and quality of care and capturing …

Heart failure (HF) is a complex syndrome that affects mortality/morbidity and acts at different
levels in the patient's life, resulting in a drastic impairment in multiple aspects of daily …

There are many consequences of heart failure (HF), including symptoms, impaired health‐
related quality of life (HRQoL), and physical and social limitations (functional status). These …

ADLs inabilities and hospitalizations is straightforward, the risk for mortality is not as clear. A
better understanding of the links between ADLs and mortality will enable targeted therapies …

The evidence base of what works in chronic care management programs is
underdeveloped. To fill the gap, we pooled and reanalyzed data from ten randomized …

Patient-reported outcomes (PROs) are any report obtained directly from a patient about how
they feel or function in relation to their health condition and its therapies. Strong support for …

The standard measurements of heart failure outcome, mortality, and hospitalization,
although important, are insufficient as they measure only the major exacerbations. In …

Older people often suffer from multiple diseases. Therefore, universal cross-disease
outcomes (eg functional status, quality of life, overall survival) are more relevant than …