Understanding the pharmacodynamics of cannabinoids is an essential subject due to the
recent increasing global acceptance of cannabis and its derivation for recreational and …

Application of cannabinoids and endocannabinoids to perfused vascular beds or individual
isolated arteries results in changes in vascular resistance. In most cases, the result is …

Cannabinoids influence cardiovascular variables in health and disease via multiple
mechanisms. The chapter covers the impact of cannabinoids on cardiovascular function in …

While cannabis is perceived as a relatively safe drug by the public, accumulating clinical
data suggest detrimental cardiovascular effects of cannabinoids. Cannabis has been …

The endocannabinoid system is widely distributed throughout the cardiovascular system.
Endocannabinoids play a minimal role in the regulation of cardiovascular function in normal …

Cardiovascular disease represents a leading cause of death, morbidity, and societal
economic burden. The prevalence of cannabis use has significantly increased due to …

Endocannabinoids are a group of arachidonic acid-derived lipid mediators binding to
cannabinoid receptors CB1 and CB2. An overactivity of the endocannabinoid system plays a …

Cannabinoids play critical roles in human pathophysiology through the cannabinoid (CB)
receptors and non-CB receptors on variety of cells, tissues, and organs. Microvasculature …

Marijuana is used by humans for its psychoactive and medicinal effects. The active
constituents of marijuana, the cannabinoids, exert effects via a G protein-coupled receptor …

Atherosclerosis and its major acute complications, myocardial infarction and stroke, are the
leading causes of death and morbidity worldwide. Despite major advances in cardiovascular …