Multiple sclerosis (MS), and its animal model experimental autoimmune encephalomyelitis,
are neuroinflammatory diseases driven by autoreactive pathogenic TH cells that elicit …

Multiple sclerosis (MS) is an autoimmune disease that affects hundreds of thousands of
people worldwide. Given the autoimmune nature of the disease, a large part of the research …

Background: Interferon (IFN)-β is an effective therapy for relapsing-remitting multiple
sclerosis, yet its mechanism of action remains ill-defined. Objectives: Our objective was to …

Multiple sclerosis (MS) is the prototypic inflammatory disease of the central nervous system
(CNS) characterized by multifocal areas of demyelination, axonal damage, activation of glial …

Abstract Background Interleukin (IL)-1β is a pro-inflammatory cytokine that plays a role in the
pathogenesis of multiple sclerosis (MS) and experimental autoimmune encephalomyelitis …

Experimental autoimmune encephalomyelitis (EAE) is an inflammatory disease of the
central nervous system (CNS) which is often used as an animal model for human multiple …

Experimental autoimmune encephalomyelitis (EAE) is a CD4+ T cell-mediated, inflammatory
demyelinating disease of the central nervous system (CNS) that serves as a model for …

IL-6 is crucial for the induction of many murine models of autoimmunity including
experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis …

The etiology of multiple sclerosis (MS) remains unknown. However, both genetic and
environmental factors play important roles in its pathogenesis. While demyelination of axons …

The role of interferon (IFN)-γ in multiple sclerosis (MS) and its animal model, experimental
autoimmune encephalomyelitis (EAE), has remained as an enigmatic paradox for more than …