[HTML][HTML] Baicalin attenuates alcoholic liver injury through modulation of hepatic oxidative stress, inflammation and sonic hedgehog pathway in rats

H Wang, Y Zhang, R Bai, M Wang, S Du - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Lipid accumulation, inflammatory responses and oxidative stress have
been implicated in the pathology of alcoholic liver disease (ALD). Targeting inhibition of …

[HTML][HTML] Soyasaponin II protects against acute liver failure through diminishing YB-1 phosphorylation and Nlrp3-inflammasome priming in mice

F Wang, S Gong, T Wang, L Li, H Luo, J Wang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Acute liver failure is characterized by the rapid development of liver dysfunction and
remarkably high mortality. Accumulating evidence suggests that soyasaponin possesses …

Lipid-lowering, anti-inflammatory, and hepatoprotective effects of isorhamnetin on acetaminophen-induced hepatotoxicity in mice

H Gungor, M Ekici, MB Ates - Drug and Chemical Toxicology, 2023 - Taylor & Francis
Isorhamnetin is a hepatoprotective flavonoid molecule derived from the leaves and fruits of
Hippophae rhamnoides L. However, the protective effect of isorhamnetin on acetaminophen …

Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration

Y Jiang, X Fan, Y Wang, P Chen, H Zeng… - Toxicological …, 2015 - academic.oup.com
Acetaminophen (APAP) overdose is the most frequent cause of drug-induced acute liver
failure. Schisandra sphenanthera is a traditional hepato-protective Chinese medicine and …

The hepatoprotective effects of Sedum sarmentosum extract and its isolated major constituent through Nrf2 activation and NF-κB inhibition

GW Wang, XL Zhang, QH Wu, YB Jin, CT Ning… - Phytomedicine, 2019 - Elsevier
Background Sedum sarmentosum, which is recorded in Chinese Pharmacopoeia, has been
applied clinically to treat liver and gallbladder diseases. Purpose This study aimed to …

Hemistepsin A ameliorates acute inflammation in macrophages via inhibition of nuclear factor-κB and activation of nuclear factor erythroid 2-related factor 2

JK Kim, JE Lee, EH Jung, JY Jung, DH Jung… - Food and chemical …, 2018 - Elsevier
Hemistepsin A (HsA) is a sesquiterpene lactone isolated from Hemistepta lyrata (Bunge)
Bunge. We investigated the anti-inflammatory effects of HsA and sought to determine its …

[PDF][PDF] Breviscapine alleviates NASH by inhibiting TGF‐β‐activated kinase 1‐dependent signaling

T Lan, S Jiang, J Zhang, Q Weng, Y Yu, H Li… - …, 2022 - Wiley Online Library
Background and Aims NAFLD is a key component of metabolic syndrome, ranging from
nonalcoholic fatty liver to NASH, and is now becoming the leading cause of cirrhosis and …

[HTML][HTML] Sweroside ameliorates α-naphthylisothiocyanate-induced cholestatic liver injury in mice by regulating bile acids and suppressing pro-inflammatory responses

Q Yang, F Yang, J Gong, X Tang, G Wang… - Acta Pharmacologica …, 2016 - nature.com
Aim: Sweroside is an iridoid glycoside with diverse biological activities. In the present study
we investigated the effects of sweroside on α-naphthylisothiocyanate (ANIT)-induced …

[HTML][HTML] Soyasaponin Bb protects rat hepatocytes from alcohol-induced oxidative stress by inducing heme oxygenase-1

Z Lijie, F Ranran, L Xiuying, H Yutang… - Pharmacognosy …, 2016 - ncbi.nlm.nih.gov
Background: It has been known that oxidative stress induced by alcohol played a crucial role
in the formation of alcoholic liver disease. Although the formation mechanisms underlying …

[HTML][HTML] Flavonoids from Scutellaria amoena CH Wright alleviate mitochondrial dysfunction and regulate oxidative stress via Keap1/Nrf2/HO-1 axis in rats with high-fat …

QL Fang, X Qiao, X Yin, Y Zeng, C Du, Y Xue… - Biomedicine & …, 2023 - Elsevier
Background Nonalcoholic steatohepatitis (NASH) is among the most common liver diseases
in the world. Flavonoids from Scutellaria amoena (SAF) are used in the treatment of …