Innate lymphoid cells and cancer

N Jacquelot, C Seillet, E Vivier, GT Belz - Nature Immunology, 2022 - nature.com
The innate lymphoid cell (ILC) family is composed of natural killer (NK) cells, ILC1, ILC2 and
ILC3, which participate in immune responses to virus, bacteria, parasites and transformed …

Tissue microenvironment dictates the fate and tumor-suppressive function of type 3 ILCs

K Nussbaum, SH Burkhard, I Ohs, F Mair… - Journal of Experimental …, 2017 - rupress.org
Innate lymphoid cells (ILCs) have been classified into “functional subsets” according to their
transcription factor and cytokine profiles. Although cytokines, such as IL-12 and IL-23, have …

Isolation and analysis of group 2 innate lymphoid cells in mice

K Moro, KN Ealey, H Kabata, S Koyasu - Nature protocols, 2015 - nature.com
Recent studies have identified distinct subsets of innate lymphocytes, collectively called
innate lymphoid cells (ILCs), which lack antigen receptor expression but produce various …

Skin-resident innate lymphoid cells–cutaneous innate guardians and regulators

T Kobayashi, RR Ricardo-Gonzalez, K Moro - Trends in immunology, 2020 - cell.com
Skin is the largest barrier organ and an important interface between the body and the
outside environment. Immune surveillance and homeostatic regulation of skin function are …

Interactions between innate and adaptive lymphocytes

G Gasteiger, AY Rudensky - Nature Reviews Immunology, 2014 - nature.com
Innate lymphocytes—including natural killer cells and the recently discovered innate
lymphoid cells—have crucial roles during infection, tissue injury and inflammation. Innate …

Natural killers or ILC1s? That is the question

C Seillet, L Brossay, E Vivier - Current opinion in immunology, 2021 - Elsevier
Group 1 innate lymphoid cells (ILCs) comprise the natural killer (NK) cells and ILC1s. Both
cells co-exist in peripheral tissues and despite effort to characterize the molecular identity …

Granzyme A and CD160 expression delineates ILC1 with graded functions in the mouse liver

C Di Censo, M Marotel, I Mattiola… - European journal of …, 2021 - Wiley Online Library
Type 1 innate lymphoid cells (ILC1) are tissue‐resident lymphocytes that provide early
protection against bacterial and viral infections. Discrete transcriptional states of ILC1 have …

Innate lymphoid cells in autoimmune diseases

AS Clottu, M Humbel, N Fluder… - Frontiers in …, 2022 - frontiersin.org
Innate lymphoid cells (ILC) are a heterogeneous group of immune cells characterized by
lymphoid morphology and cytokine profile similar to T cells but which do not express clonally …

Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages

CSN Klose, M Flach, L Möhle, L Rogell, T Hoyler… - Cell, 2014 - cell.com
Innate lymphoid cells (ILCs) are a recently recognized group of lymphocytes that have
important functions in protecting epithelial barriers against infections and in maintaining …

Polychromic reporter mice reveal unappreciated innate lymphoid cell progenitor heterogeneity and elusive ILC3 progenitors in bone marrow

JA Walker, PA Clark, A Crisp, JL Barlow, A Szeto… - Immunity, 2019 - cell.com
Innate lymphoid cells (ILCs) play strategic roles in tissue homeostasis and immunity. ILCs
arise from lymphoid progenitors undergoing lineage restriction and the development of …