Breast cancer resistance likelihood and personalized treatment through integrated multiomics

S Mehmood, M Faheem, H Ismail, SM Farhat… - Frontiers in Molecular …, 2022 - frontiersin.org
In recent times, enormous progress has been made in improving the diagnosis and
therapeutic strategies for breast carcinoma, yet it remains the most prevalent cancer and …

Breast cancer genomes—form and function

J Korkola, JW Gray - Current opinion in genetics & development, 2010 - Elsevier
This review summarizes advances in our understanding of the genomic and epigenomic
abnormalities in breast cancers that are being revealed by the increasingly powerful suite of …

Genomics-based prognosis and therapeutic prediction in breast cancer

SS Jeffrey, PE Lønning, BE Hillner - Journal of the National …, 2005 - jnccn.org
Breast cancer is a heterogeneous disease. DNA microarray technology is being applied to
breast cancer to identify new prognostic biomarkers, to predict response to therapy, and to …

Genetics and Genomics of Breast Cancer: update and translational perspectives

M Biancolella, B Testa, LB Salehi, MR D'Apice… - Seminars in cancer …, 2021 - Elsevier
In the recent years the rapid scientific innovation in the evaluation of the individual's genome
have allowed the identification of variants associated with the onset, treatment and …

[HTML][HTML] New targeted therapies for breast cancer: A focus on tumor microenvironmental signals and chemoresistant breast cancers

AHN Kamdje, PFS Etet, L Vecchio… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Breast cancer is the most frequent female malignancy worldwide. Current strategies in
breast cancer therapy, including classical chemotherapy, hormone therapy, and targeted …

Breast cancer—one term, many entities?

NR Bertos, M Park - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Breast cancer, rather than constituting a monolithic entity, comprises heterogeneous tumors
with different clinical characteristics, disease courses, and responses to specific treatments …

Identifying breast cancer druggable oncogenic alterations: lessons learned and future targeted options

A Ocana, A Pandiella - Clinical Cancer Research, 2008 - AACR
Although the introduction of novel therapies and drug combinations has improved the
prognosis of metastatic breast cancer, this disease remains incurable. It is therefore …

Cellular plasticity in breast cancer progression and therapy

D Kong, CJ Hughes, HL Ford - Frontiers in molecular biosciences, 2020 - frontiersin.org
With the exception of non-melanoma skin cancer, breast cancer is the most frequently
diagnosed malignant disease among women, with the majority of mortality being attributable …

Molecular oncology of breast cancer

H Joshi, MF Press - The Breast, 2018 - Elsevier
Breast cancer, like other cancers, is a genetic disease. The disease is caused by acquired
molecular alterations during the lifetime of an individual and by inherited mutant genes. Risk …

DNA repair and personalized breast cancer therapy

SX Li, A Sjolund, L Harris… - Environmental and …, 2010 - Wiley Online Library
Personalized cancer therapy is likely to be one of the next big advances in our search for a
cure for cancer. To be able to treat people in an individualized manner, researchers need to …