Increased circulating Th17 cells, serum IL‐17A, and IL‐23 in Takayasu arteritis

DP Misra, S Chaurasia, R Misra - Autoimmune diseases, 2016 - Wiley Online Library
Introduction. Th17, γδT, NK, and NKT cells in peripheral blood and serum IL‐17 and IL‐23 in
Takayasu arteritis (TA) were measured and correlated with disease activity. Methods. Th17 …

Novel Th17 lymphocyte populations, Th17. 1 and PD1+ Th17, are increased in Takayasu arteritis, and both Th17 and Th17. 1 sub-populations associate with active …

K Singh, U Rathore, MK Rai, MR Behera… - Journal of …, 2022 - Taylor & Francis
Purpose We evaluated T helper lymphocyte profile, including novel Th17 subsets Th17. 1
(secrete IFN-γ, associate with corticosteroid resistance) and PD1+ Th17 (secrete TGF-β1 …

Th1 and Th17 cytokines drive inflammation in Takayasu arteritis

D Saadoun, M Garrido, C Comarmond… - Arthritis & …, 2015 - Wiley Online Library
Objective Takayasu arteritis (TAK) is a large‐vessel vasculitis that induces damage to the
aorta and its branches. Glucocorticoids remain the gold standard of therapy for TAK. The …

IL-9-producing Th9 cells may participate in pathogenesis of Takayasu's arteritis

L Pan, J Du, N Gao, H Liao, J Wan, W Ci, C Yang… - Clinical …, 2016 - Springer
Takayasu's arteritis (TAK) is a type of large vessel vasculitis which involves the aorta and its
major branches. Interleukin (IL)-9 or IL-9-producing Th9 cells were found to be involved in …

Correlation of peripheral Th17 cells and Th17-associated cytokines to the severity of carotid artery plaque and its clinical implication

Z Liu, F Lu, H Pan, Y Zhao, S Wang, S Sun, J Li, X Hu… - Atherosclerosis, 2012 - Elsevier
OBJECTIVE: Atherosclerosis is a chronic inflammatory disease regulated by T lymphocyte
subsets. Th17 cells reportedly play important roles in the development of inflammatory and …

[HTML][HTML] Decreased absolute number of circulating regulatory T cells in patients with Takayasu's arteritis

W Jia, ZL Fu, X Wang, J Luo, CL Yan, JP Cao… - Frontiers in …, 2021 - frontiersin.org
Background Takayasu's arteritis (TA) is a type of primary large vessel vasculitis. Th1, Th17,
and Tfh cells have been reported to be associated with TA relapse. However, the …

[PDF][PDF] The critical role of IL-6 in the pathogenesis of Takayasu arteritis

X Kong, Y Sun, L Ma, H Chen, L Wei, W Wu… - Clin Exp …, 2016 - clinexprheumatol.org
Objective. To investigate T cell subsets and immune cytokine profiles in untreated Takayasu
arteritis (TAK) patients and the underlying immunopathological mechanism. Methods. We …

[PDF][PDF] Silent arterial inflammation during the apparent remission state of Takayasu's arteritis. What do cytokines tell us

B Savioli, BR Salu, MV de Brito… - Clin Exp …, 2018 - clinexprheumatol.org
Objective. To evaluate serum cytokines as biomarkers of smoldering disease activity in
patients with Takayasu's arteritis (TAK) in remission. Methods. Thirty-four TAK patients with …

Increased Th17 cells in coronary artery disease are associated with neutrophilic inflammation

Z Wang, J Lee, Y Zhang, H Wang, X Liu… - Scandinavian …, 2011 - Taylor & Francis
Objective. Atherosclerosis is a progressive disease characterized by a series of
inflammatory responses in the large and medium arteries. Th17 cells, a distinct T cell …

Are cytokines and chemokines suitable biomarkers for Takayasu arteritis?

B Savioli, WH Abdulahad, E Brouwer… - Autoimmunity …, 2017 - Elsevier
There is a growing need for disease related biomarkers in Takayasu arteritis (TA). The
assessment of pro-inflammatory cytokines and chemokines in TA may provide a better …