Animals constantly perceive and integrate information across sensory modalities, and their
nervous systems must select behavioral responses appropriate to the current situation and …

Animals constantly integrate sensory information with prior experience to select behavioral
responses appropriate to the current situation. Genetic factors supporting this behavioral …

Animal models are instrumental to understanding the mechanisms underlying autism
spectrum disorder, yet translating human behavioral phenotypes remains challenging …

Habituation is a foundational learning process critical for animals to adapt their behavior to
changes in their sensory environment. Although habituation is considered a simple form of …

Methods: We used CRISPR/Cas9 to introduce frameshift mutations in the syngap1a and
syngap1b zebrafish duplicates (syngap1ab) and validated these stable models for Syngap1 …

Habituation is a foundational learning process critical for animals to adapt their behavior to
changes in their sensory environment. Although habituation is considered a simple form of …

Autism spectrum disorders (ASDs) are characterized by abnormal behavioral traits arising
from neural circuit dysfunction. While a number of genes have been implicated in ASDs, in …

Neural systems encode information in the frequency of action potentials, which is then
decoded by synaptic transmission. However, the rapid, synchronous release of …

Neurons express adaptor (AP)-3 complexes assembled with either ubiquitous (β3A) or
neuronal-specific (β3B) β3 isoforms. However, it is unknown whether these complexes …

Background Although habituation is one of the most ancient and fundamental forms of
learning, its regulators and relevance for human disease are poorly understood. Methods …