Restoring the tooth-supporting tissues lost during periodontitis is a significant clinical
challenge, despite advances in both biomaterial and cell-based approaches. This study …

Periodontal bone defect is a common but longstanding healthcare issue since traditional
bone grafts have limited functionalities in regulating complex intraoral microenvironments …

Background The aim of this study was to construct crosslinked polylysine‐hyaluronic acid
microspheres (pl‐HAM) ladened with gingival mesenchymal stem cells (GMSCs) and …

Periodontitis is an inflammatory disease characterized by tooth‐supporting periodontal
tissue destruction, including the cementum, periodontal ligament, and alveolar bone. To …

Background Tissue-engineering strategies based on mesenchymal stem cells (MSCs) and
cell sheets have been widely used for periodontal tissue regeneration. However, given the …

Periodontal regeneration involves the restoration of at least three unique tissues: cementum,
periodontal ligament tissue (PDL) and alveolar bone tissue. Here, we first isolated human …

Cartilage tissue regeneration often presents a challenging clinical situation. Recently, it has
been shown that Periodontal Ligament Stem Cells (PDLSCs) possess high chondrogenic …

This study is aimed to evaluate the in vivo biocompatibility and periodontal regenerative
potential of enzymatically solidified chitosan hydrogels with or without incorporated …

This study reports on scaffold-based periodontal tissue engineering in a large preclinical
animal model. A biphasic scaffold consisting of bone and periodontal ligament …

Background A nanohydroxyapatite-coated chitosan scaffold has been developed in recent
years, but the effect of this composite scaffold on the viability and differentiation of …