Objective The aim of this study was to examine the potential of periodontal ligament (PDL)
cells sheet and arginine-glycyl-aspartic acid (RGD)-modified chitosan scaffold for …

Periodontitis is a chronic inflammatory disease that induces the destruction of tooth-
supporting tissues, followed by tooth loss. Although several approaches have been applied …

The guided tissue regeneration (GTR) technique is a promising treatment for periodontal
tissue defects. GTR membranes build a mechanical barrier to control the ingrowth of the …

The repair or regeneration of well-aligned periodontal ligaments (PDL) remains a
challenging clinical task in reconstructive surgeries and regenerative medicine …

The aim of this study was to compare the osteogenic effects of periodontal ligament stem
cells (PDLSCs) versus bone marrow mesenchymal stem cells (BMMSCs) in combination …

Background The regeneration of periodontal bone defect remains a vital clinical challenge.
To date, numerous biomaterials have been applied in this field. However, the immune …

Periodontitis, a widespread disease, is the main cause of tooth loss in adults, and there is no
ideal clinical therapy for patients with severe alveolar bone defects. Research investigating …

Hydrogels have been widely applied to the fabrication of tissue engineering scaffolds via
three-dimensional (3D) bioprinting because of their extracellular matrix-like properties …

Regeneration of periodontal tissue remains a challenge. Under periodontitis, osteoclasts are
overactivated and bone loss occurs. We incorporated sodium alendronate (Alen), a …

Periodontitis is a worldwide chronic inflammatory disease, where surgical treatment still
shows an uncertain prognosis. To break through the dilemma of periodontal treatment, we …