The success of tissue-engineering therapies is dependent on the ability of scaffolds to guide
differentiation of progenitor cells. Here we present a new approach using a biomimetic …

Hydrogel, a functional polymer material, has emerged as a promising technology for
therapies for periodontal diseases. It has the potential to mimic the extracellular matrix and …

Periodontal defect seriously affects people's life health and quality. Guided tissue
regeneration (GTR) and guided bone regeneration (GBR) have made great progress in …

Background Barrier membranes and bone substitute are major tools of guided tissue
regeneration (GTR) after periodontal disease. Integrity of the periodontal ligament plays a …

Introduction Human periodontal ligament mesenchymal stem cells (hPDLMSCs) have been
known that they play important roles in homeostasis and regeneration of periodontal tissues …

Periodontal tissues are organized in a complex three-dimensional (3D) architecture,
including the alveolar bone, cementum, and a highly aligned periodontal ligament (PDL) …

Aim Due to a lack of regenerative potential, current treatments for periodontal defects do not
always provide satisfactory clinical results. Previously, the implantation of a biomaterial …

Periodontal ligament stem cells (PDLSCs) possess extensive regeneration potential.
However, their therapeutic application demands a scaffold with appropriate properties …

Periodontium is a complex structure that supports the teeth, composed of gingiva,
cementum, periodontal ligament, and alveolar bone. Destruction of the alveolar bone can …

Human periodontal ligament fibroblasts (hPDLF) play a key role in the regeneration of
periodontal compartment during guided tissue regeneration procedures. This property is …