[HTML][HTML] Androgen receptor and soy isoflavones in prostate cancer

MK Sivoňová, P Kaplán… - Molecular and …, 2019 - spandidos-publications.com
Androgens and androgen receptor (AR) play a critical role not only in normal prostate
development, but also in prostate cancer. For that reason, androgen deprivation therapy …

[HTML][HTML] The Use of Soy Isoflavones in the Treatment of Prostate Cancer: A Focus on the Cellular Effects

H Van der Eecken, S Joniau, C Berghen, K Rans… - Nutrients, 2023 - mdpi.com
A possible link between diet and cancer has long been considered, with growing interest in
phytochemicals. Soy isoflavones have been associated with a reduced risk of prostate …

Soy isoflavones and prostate cancer: a review of molecular mechanisms

AM Mahmoud, W Yang, MC Bosland - The Journal of steroid biochemistry …, 2014 - Elsevier
Soy isoflavones are dietary components for which an association has been demonstrated
with reduced risk of prostate cancer (PCa) in Asian populations. However, the exact …

Genistein and daidzein: different molecular effects on prostate cancer

M Adjakly, M Ngollo, JP Boiteux, YJ Bignon… - Anticancer …, 2013 - ar.iiarjournals.org
Diet is believed to play an important role in cancer. It has been revealed by epidemiological
studies that Asian populations, who consume phytoestrogens in large amounts, have a …

Perspectives on the role of isoflavones in prostate cancer

A Ahmad, B Biersack, Y Li, B Bao, D Kong, S Ali… - The AAPS journal, 2013 - Springer
Isoflavones have been investigated in detail for their role in the prevention and therapy of
prostate cancer. This is primarily because of the overwhelming data connecting high dietary …

The role of soy phytoestrogens in prostate cancer

JM Holzbeierlein, J McIntosh… - Current opinion in …, 2005 - journals.lww.com
After reading this review, we expect that the reader will understand the background of the
isoflavones, the effect they exert at the molecular level, and their proposed benefits and …

Combination of low dose of genistein and daidzein has synergistic preventive effects on isogenic human prostate cancer cells when compared with individual soy …

X Dong, W Xu, RA Sikes, C Wu - Food chemistry, 2013 - Elsevier
The reduced incidence of prostate cancer (PCa) in Asia countries has been attributed to
high soy diets, and major soy isoflavones, in particular daidzein and genistein, are thought …

An overview of the health effects of isoflavones with an emphasis on prostate cancer risk and prostate-specific antigen levels

M Messina, O Kucuk, JW Lampe - Journal of AOAC International, 2006 - academic.oup.com
Soybean isoflavones possess hormonal and nonhormonal properties that may reduce the
risk of coronary heart disease, osteoporosis, and certain cancers, and alleviate hot flashes in …

Clinical pharmacology of isoflavones and its relevance for potential prevention of prostate cancer

PL De Souza, PJ Russell, JH Kearsley… - Nutrition …, 2010 - academic.oup.com
Isoflavones are phytoestrogens that have pleiotropic effects in a wide variety of cancer cell
lines. Many of these biological effects involve key components of signal transduction …

The role of soy phytoestrogens in prostate cancer

EP Castle, JB Thrasher - Urologic Clinics, 2002 - urologic.theclinics.com
There has been growing interest in the preventive and therapeutic effects of diet on various
cancers affecting the breast, colon, and prostate. The beneficial effects of soy on prostate …