Coronary artery disease (CAD) is a leading cause of death worldwide and frequently
associated with mitochondrial dysfunction. Detailed understanding of abnormalities in …

Coronary heart disease (CHD) is the major cause of death in modern society. CHD is
characterized by atherosclerosis, which could lead to vascular cavity stenosis or obstruction …

The heart is highly dependent for its function on oxidative energy generated in mitochondria,
primarily by fatty acid beta-oxidation, respiratory electron chain and oxidative …

Rationale: Mitochondrial dysfunction plays a pivotal role in the development of heart failure.
Animal studies suggest that impaired mitochondrial biogenesis attributable to …

Atherosclerosis is a multifactorial inflammatory pathology that involves metabolic processes.
Improvements in therapy have drastically reduced the prognosis of cardiovascular disease …

Mitochondria provide energy to the cell during aerobic respiration by supplying~ 95% of the
adenosine triphosphate (ATP) molecules via oxidative phosphorylation. These organelles …

High mortality rates due to cardiovascular diseases (CVDs) have attracted worldwide
attention. It has been reported that mitochondrial dysfunction is one of the most important …

The role of mitochondria in cardiovascular diseases is receiving ever growing attention. As a
central player in the regulation of cellular metabolism and a powerful controller of cellular …

Mitochondria in the heart play two roles essential for cell survival: ATP synthesis and
maintenance of Ca 2+ homeostasis. These two processes are driven by the same energy …

Objective: Defects in mitochondrial structure and function have been found in association
with cardiovascular diseases such as dilated and hypertrophic cardiomyopathy, cardiac …