[HTML][HTML] Pulsed electromagnetic field stimulation of bone healing and joint preservation: cellular mechanisms of skeletal response

R Cadossi, L Massari, J Racine-Avila… - … Global Research & …, 2020 - journals.lww.com
The US FDA has approved pulsed electromagnetic fields (PEMFs) as a safe and effective
treatment for nonunions of bone. Despite its clinical use, the mechanisms of action of …

Underlying signaling pathways and therapeutic applications of pulsed electromagnetic fields in bone repair

J Yuan, F Xin, W Jiang - Cellular Physiology and Biochemistry, 2018 - karger.com
Pulsed electromagnetic field (PEMF) stimulation, as a prospective, noninvasive, and safe
physical therapy strategy to accelerate bone repair has received tremendous attention in …

Stimulation of bone formation and fracture healing with pulsed electromagnetic fields: biologic responses and clinical implications

B Chalidis, N Sachinis, A Assiotis… - International journal …, 2011 - journals.sagepub.com
Pulsed electromagnetic fields (PEMF) have been used for several years to supplement bone
healing. However, the mode of action of this non-invasive method is still debated and …

Pulsed electro-magnetic field (pemf) effect on bone healing in animal models: a review of its efficacy related to different type of damage

M Di Bartolomeo, F Cavani, A Pellacani, A Grande… - Biology, 2022 - mdpi.com
Simple Summary Pulsed electromagnetic fields (PEMFs) are a type of biophysical
stimulation that has been shown to be effective in improving bone regeneration and …

Stimulation of osteogenic differentiation in human osteoprogenitor cells by pulsed electromagnetic fields: an in vitro study

JHW Jansen, OP van der Jagt, BJ Punt… - BMC musculoskeletal …, 2010 - Springer
Background Although pulsed electromagnetic field (PEMF) stimulation may be clinically
beneficial during fracture healing and for a wide range of bone disorders, there is still debate …

The role of electrical stimulation in bone repair

DMK Ciombor, RK Aaron - Foot and ankle clinics, 2005 - foot.theclinics.com
Electric and electromagnetic fields regulate the expression of genes for extracellular matrix
proteins in connective tissue cells. In vitro, this process has been observed in limb …

Pulsed electromagnetic field stimulation in osteogenesis and chondrogenesis: signaling pathways and therapeutic implications

K Varani, F Vincenzi, S Pasquini, I Blo, S Salati… - International Journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) are the main cell players in tissue repair and thanks to their
self-renewal and multi-lineage differentiation capabilities, they gained significant attention …

Translational insights into extremely low frequency pulsed electromagnetic fields (ELF-PEMFs) for bone regeneration after trauma and orthopedic surgery

S Ehnert, S Schröter, RH Aspera-Werz, W Eisler… - Journal of clinical …, 2019 - mdpi.com
The finding that alterations in electrical potential play an important role in the mechanical
stimulation of the bone provoked hype that noninvasive extremely low frequency pulsed …

Pulsed electromagnetic fields and tissue engineering of the joints

K Iwasa, AH Reddi - Tissue Engineering Part B: Reviews, 2018 - liebertpub.com
Background: Bone and joint formation, maintenance, and regeneration are regulated by
both chemical and physical signals. Among the physical signals there is an increasing …

[HTML][HTML] Effects of electromagnetic fields on osteoarthritis

T Wang, W Xie, W Ye, C He - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Osteoarthritis (OA), characterized by joint malfunction and chronic disability, is the most
common form of arthritis. The pathogenesis of OA is unclear, yet studies have shown that it is …