As acute hepatitis C virus (HCV) infection is clinically inapparent in most cases, the
immunologic correlates of recovery are not well defined. The cellular immune response is …

The hepatitis C virus (HCV) persists in the majority of infected individuals and is a significant
cause of human illness and death globally. Recent studies have yielded important insights …

In 1975, as the prospective studies continued, my attention was directed at proving NANB
hepatitis transmission in the chimpanzee model. Earlier attempts at chimpanzee …

Spontaneous resolution of hepatitis C virus (HCV) infection in humans usually affords long-
term immunity to persistent viremia and associated liver diseases. Here, we report that …

A major problem in hepatitis C virus (HCV) immunotherapy or vaccine design is the extreme
variability of the virus. We identified human monoclonal antibodies (mAbs) that neutralize …

In chronic hepatitis C virus (HCV) infection, exhausted HCV-specific CD8+ T cells comprise
memory-like and terminally exhausted subsets. However, little is known about the molecular …

Three percent of the world's population is chronically infected with the hepatitis C virus
(HCV) and at risk of developing liver cancer. Effective cellular immune responses are …

Perspective: Test and treat this silent killer | Nature Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the best …

Worldwide, an estimated 185 million people have been infected with the hepatitis C virus
(HCV). Untreated, the infection can lead to cirrhosis, liver failure, and liver cancer, causing …

Since the discovery of the hepatitis C virus over 15 years ago, scientists have raced to
develop diagnostics, study the virus and find new therapies. Yet virtually every attempt to …