Screening hepatoblastoma in Beckwith-Wiedemann syndrome: a complex issue

A Mussa, GB Ferrero - Journal of Pediatric Hematology/Oncology, 2015 - journals.lww.com
Trobaugh-Lotrario et al 1 are to be congratulated on their detailed review of cases of
Beckwith-Wiedemann Syndrome (BWS) with hepatoblastoma. We think that details …

Congenital hepatoblastoma and Beckwith-Wiedemann syndrome

A Zivot, M Edelman, R Glick, A Hong… - Journal of Pediatric …, 2020 - journals.lww.com
Following the discovery of a fetal hepatic tumor, labor was induced at 38 weeks, and a
phenotypically normal female was delivered vaginally. A serum alpha-fetoprotein level at …

Phenotype, cancer risk, and surveillance in Beckwith–Wiedemann syndrome depending on molecular genetic subgroups

SM Maas, F Vansenne, DJM Kadouch… - American journal of …, 2016 - Wiley Online Library
Patients with Beckwith–Wiedemann syndrome (BWS) have an increased risk to develop
cancer in childhood, especially Wilms tumor and hepatoblastoma. The risk varies depending …

Simultaneous presentation of Wilms tumor and immature ovarian teratoma in Beckwith-Wiedemann syndrome

JC White, J Liu, A Nahar - Journal of pediatric hematology …, 2018 - journals.lww.com
Abstract The Beckwith-Wiedemann syndrome is a cancer predisposition syndrome
characterized by a predilection to embryonal tumor growth, especially Wilms tumor …

Acute lymphocytic leukaemia in a child with Beckwith–Wiedemann syndrome harbouring a CDKN1C mutation

C Abadie, F Bernard, I Netchine, D Sanlaville… - European Journal of …, 2010 - Elsevier
Beckwith–Wiedemann syndrome (BWS) is a rare overgrowth syndrome associated with an
increased risk in childhood tumours. The phenotypic variability in BWS reflects its molecular …

Hepatoblastoma in children with Beckwith-Wiedemann syndrome: does it warrant different treatment?

AD Trobaugh-Lotrario, R Venkatramani… - Journal of pediatric …, 2014 - journals.lww.com
Abstract Patients with Beckwith-Wiedemann Syndrome (BWS) are predisposed to
developing hepatoblastoma. Clinical data were reviewed in all cases of hepatoblastoma in …

Cancer risk in Beckwith-Wiedemann syndrome: a systematic review and meta-analysis outlining a novel (Epi) genotype specific histotype targeted screening protocol

A Mussa, C Molinatto, G Baldassarre, E Riberi… - The Journal of …, 2016 - Elsevier
Objective To compare tumor risk in the 4 Beckwith-Wiedemann syndrome (BWS) molecular
subgroups: Imprinting Control Region 1 Gain of Methylation (ICR1-GoM), Imprinting Control …

[HTML][HTML] Genomic profiles of a hepatoblastoma from a patient with Beckwith-Wiedemann syndrome with uniparental disomy on chromosome 11p15 and germline …

SY Kim, SH Jung, MS Kim, MR Han, HC Park… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Beckwith-Wiedemann syndrome (BWS) is a congenital overgrowth disorder mainly
associated with altered genomic imprinting at chromosome 11p15. 5. Children with BWS …

[HTML][HTML] Molecular basis of Beckwith–Wiedemann syndrome spectrum with associated tumors and consequences for clinical practice

T Eggermann, ER Maher, CP Kratz, D Prawitt - Cancers, 2022 - mdpi.com
Simple Summary Beckwith–Wiedemann syndrome (BWS, OMIM 130650) is an inborn
overgrowth disorder caused by molecular alterations in chromosome 11p15. 5. These …

Neonatal hepatoblastoma in a newborn with severe phenotype of Beckwith–Wiedemann syndrome

A Mussa, GB Ferrero, B Ceoloni, E Basso… - European journal of …, 2011 - Springer
Beckwith–Wiedemann syndrome is an overgrowth disorder characterized by neonatal
macrosomia, abdominal wall defects, macroglossia, renal anomalies, organomegaly …