Background Allogeneic skin recovered from human deceased donors (HDD) has been a
mainstay interim treatment for severe burns, but unfortunately risk of infectious disease and …

Vital, genetically engineered porcine skin transplants have long been regarded as a
promising treatment option for severe burn wounds. The objective of this two-part, preclinical …

Background The current standard of care for burns requiring operative treatment consists of
early burn excision and autologous split-thickness skin grafting. However, in large burns …

Burn is associated with a considerable burden of morbidity worldwide. Early excision of
burned tissue and skin grafting of the resultant wound has been established as a mainstay …

Temporary coverage of severely burned patients with cadaver allograft skin represents an
important component of burn care, but is limited by availability and cost. Porcine skin shares …

Weiner J, Yamada K, Ishikawa Y, Moran S, Etter J, Shimizu A, Smith RN, Sachs DH.
Prolonged survival of GalT‐KO swine skin on baboons. Xenotransplantation 2010; 17: 147 …

Half a million patients in the USA alone require treatment for burns annually. Following an
extensive burn, it may not be possible to provide sufficient autografts in a single setting. Pig …

Cadaveric skin allograft is the current standard of treatment for temporary coverage of large
burn wounds. Porcine xenografts are viable alternatives but undergo α-1, 3-galactose (Gal) …

Skin xenotransplantation: technological advances and future... : Current Opinion in Organ
Transplantation Skin xenotransplantation: technological advances and future directions …

Burns are tissue wounds caused by thermal, electrical, chemical cold or radiation injuries.
Deep injuries lead to dermal damage that impairs the ability of the skin to heal and …