MicroRNA-21-5p promotes mucosal type 2 inflammation via regulating GLP1R/IL-33 signaling in chronic rhinosinusitis with nasal polyps
G Luan, M Wang, J Yuan, X Bu, Y Wang, S Ying… - Journal of Allergy and …, 2022 - Elsevier
Background It has been known that chronic rhinosinusitis with nasal polyps (CRSwNP) is a
type 2 inflammation–dominated disease; however, the reasons causing such type of …
type 2 inflammation–dominated disease; however, the reasons causing such type of …
Elevated microRNA-21 is a brake of inflammation involved in the development of nasal polyps
R Liu, J Du, J Zhou, B Zhong, L Ba, J Zhang… - Frontiers in …, 2021 - frontiersin.org
Background CRSwNP is an inflammatory disease but the mechanism is not yet fully
understood. MiR-21, a member of miRNAs, has been reported to play roles in mediating …
understood. MiR-21, a member of miRNAs, has been reported to play roles in mediating …
MiR-214 expression is elevated in chronic rhinosinusitis mucosa and regulates lipopolysaccharide-mediated responses in undifferentiated human nasal epithelial cell …
Z Wang, D Lin, Y Zhao, H Liu… - American Journal of …, 2023 - journals.sagepub.com
Background Chronic rhinosinusitis (CRS) is an inflammatory disorder of the upper airways.
MicroRNAs (miRs) are reported to regulate several diverse physiological and pathological …
MicroRNAs (miRs) are reported to regulate several diverse physiological and pathological …
MicroRNA‑16 inhibits interleukin‑13‑induced inflammatory cytokine secretion and mucus production in nasal epithelial cells by suppressing the IκB kinase β/nuclear …
Y Gao, Z Yu - Molecular Medicine Reports, 2018 - spandidos-publications.com
Chronic inflammation of the nasal mucosal tissue plays important roles in the pathogenesis
of allergic rhinitis (AR). Aberrantly expressed microRNAs (miRNAs) have been found to …
of allergic rhinitis (AR). Aberrantly expressed microRNAs (miRNAs) have been found to …
Differential expression of miR‑4492 and IL‑10 is involved in chronic rhinosinusitis with nasal polyps
L Li, J Feng, D Zhang, J Yong… - Experimental and …, 2019 - spandidos-publications.com
Chronic rhinosinusitis (CRS) is one of the most common types of respiratory disease and
affects a large proportion of the population worldwide. The clinical differences between CRS …
affects a large proportion of the population worldwide. The clinical differences between CRS …
miR-143 inhibits interleukin-13-induced inflammatory cytokine and mucus production in nasal epithelial cells from allergic rhinitis patients by targeting IL13Rα1
Y Teng, R Zhang, C Liu, L Zhou, H Wang… - Biochemical and …, 2015 - Elsevier
Allergic rhinitis (AR) is a common chronic inflammatory condition of the nasal mucosal
tissue. The interleukin-13 (IL-13) signaling pathway is of great importance in the …
tissue. The interleukin-13 (IL-13) signaling pathway is of great importance in the …
MicroRNAs regulating mucin type O‐glycan biosynthesis and transforming growth factor β signaling pathways in nasal mucosa of patients with chronic rhinosinusitis …
L Xuan, G Luan, Y Wang, F Lan… - International forum of …, 2019 - Wiley Online Library
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent sinonasal
mucosa inflammatory disease. MicroRNAs (miRNAs) that are involved in the pathogenesis …
mucosa inflammatory disease. MicroRNAs (miRNAs) that are involved in the pathogenesis …
Up-regulation of microRNA-335-5p reduces inflammation via negative regulation of the TPX2-mediated AKT/GSK3β signaling pathway in a chronic rhinosinusitis …
X Gu, X Yao, D Liu - Cellular Signalling, 2020 - Elsevier
Chronic rhinosinusitis (CRS) is featured with chronic symptoms of inflammation or infection
in the nasal and sinus tissues. MicroRNAs (miRNAs/miRs), such as dysregulated expression …
in the nasal and sinus tissues. MicroRNAs (miRNAs/miRs), such as dysregulated expression …
Overexpression of miR-125b, a novel regulator of innate immunity, in eosinophilic chronic rhinosinusitis with nasal polyps
Rationale: Eosinophilic chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP)
represents a hard-to-treat subtype of CRS. Objectives: To determine the pattern of …
represents a hard-to-treat subtype of CRS. Objectives: To determine the pattern of …
Knockdown of miR‑205‑5p alleviates the inflammatory response in allergic rhinitis by targeting B‑cell lymphoma 6
S Zhang, S Lin, Q Tang, Z Yan - Molecular Medicine …, 2021 - spandidos-publications.com
Allergic rhinitis (AR) is an IgE‑mediated upper airway disease with a high worldwide
prevalence. MicroRNA (miR)‑205‑5p upregulation has been observed in AR; however, its …
prevalence. MicroRNA (miR)‑205‑5p upregulation has been observed in AR; however, its …