Ethanol inhibits pancreatic projecting neurons in the dorsal motor nucleus of the vagus

BN Keller, PA Randall, AC Arnold, KN Browning… - Brain Research …, 2022 - Elsevier
Alcohol use disorder (AUD) is a rapidly growing concern in the United States. Current
trending escalations of alcohol use are associated with a concurrent rise in alcohol-related …

Ethanol excitation of dopaminergic ventral tegmental area neurons is blocked by quinidine

SB Appel, Z Liu, MA McElvain, MS Brodie - Journal of Pharmacology and …, 2003 - ASPET
The dopaminergic (DA) neurons in the ventral tegmental area (VTA) are important for the
reinforcing effects of ethanol. We have shown that ethanol directly excites DA VTA neurons …

Ethanol inhibition of m-current and ethanol-induced direct excitation of ventral tegmental area dopamine neurons

S Koyama, MS Brodie… - Journal of …, 2007 - journals.physiology.org
Ethanol-induced excitation of ventral tegmental area dopamine (DA VTA) neurons is thought
to be critical for the reinforcing effects of ethanol. Although ligand-gated ion channels are …

Ethanol has concentration-dependent effects on hypothalamic POMC neuronal excitability

JM Leyrer-Jackson, EK Nagy, LE Hood, JM Newbern… - Alcohol, 2020 - Elsevier
Alcohol abuse is a worldwide public health concern, yet the precise molecular targets of
alcohol in the brain are still not fully understood. Alcohol may promote its euphoric and …

[HTML][HTML] An ultrastructural analysis of the effects of ethanol self-administration on the hypothalamic paraventricular nucleus in rhesus macaques

VA Jimenez, CM Helms, A Cornea… - Frontiers in Cellular …, 2015 - frontiersin.org
A bidirectional relationship between stress and ethanol exists whereby stressful events are
comorbid with problematic ethanol use and prolonged ethanol exposure results in …

GABAergic actions mediate opposite ethanol effects on dopaminergic neurons in the anterior and posterior ventral tegmental area

Y Guan, C Xiao, K Krnjević, G Xie, W Zuo… - Journal of Pharmacology …, 2012 - ASPET
It is known that the posterior ventral tegmental area (p-VTA) differs from the anterior VTA (a-
VTA) in that rats learn to self-administer ethanol into the p-VTA, but not into the a-VTA …

Withdrawal from intermittent ethanol exposure increases probability of burst firing in VTA neurons in vitro

FW Hopf, M Martin, BT Chen… - Journal of …, 2007 - journals.physiology.org
Changing the activity of ventral tegmental area (VTA) dopamine neurons from pacemaker to
burst firing is hypothesized to increase the salience of stimuli, such as an unexpected …

The effects of ethanol on dopaminergic neurons of the ventral tegmental area studied with intracellular recording in brain slices

MS Brodie, SB Appel - Alcoholism: Clinical and Experimental …, 1998 - Wiley Online Library
Dopaminergic neurons in the ventral tegmental area of Tsai (VTA) have been implicated in
the mediation of the rewarding effects of ethanol and many other drugs of abuse. Our …

Norepinephrine effects on identified neurons of the rat dorsal motor nucleus of the vagus

IMP y Valenzuela, RC Rogers… - American Journal …, 2004 - journals.physiology.org
The dorsal motor nucleus of the vagus (DMV) receives more noradrenergic terminals than
any other medullary nucleus; few studies, however, have examined the effects of …

Glutamate transmission to ventral tegmental area GABA neurons is altered by acute and chronic ethanol

SB Williams, JT Yorgason, AC Nelson… - Alcoholism: Clinical …, 2018 - Wiley Online Library
Background Ventral tegmental area (VTA) GABA neurons have been heavily implicated in
alcohol reinforcement and reward. In animals that self‐administer alcohol, VTA GABA …