[HTML][HTML] The role of testosterone and gibberellic acid in the melanization of Cryptococcus neoformans

JS Tucker, TE Guess, EE McClelland - Frontiers in Microbiology, 2020 - frontiersin.org
Cryptococcus neoformans, a spore-producing pathogenic yeast, affects
immunocompromised individuals causing meningoencephalitis. Once C. neoformans is …

Cryptococcus neoformans/Cryptococcus gattii species complex melanized by epinephrine: Increased yeast survival after amphotericin B exposure

RSN Brilhante, MG da Rocha, JS de Oliveira… - Microbial …, 2020 - Elsevier
Cryptococcus neoformans/Cryptococcus gattii complex species are etiological agents of
cryptococcosis, a systemic mycosis that cause respiratory infection and …

[HTML][HTML] Genetic Factors and Genotype-Environment Interactions Contribute to Variation in Melanin Production in the Fungal Pathogen Cryptococcus neoformans

H Samarasinghe, D Aceituno-Caicedo, M Cogliati… - Scientific reports, 2018 - nature.com
Cryptococcosis is a common opportunistic fungal infection that often disseminates into the
central nervous system, leading to meningitis. Production of melanin pigments during …

[HTML][HTML] Role of Cln1 during melanization of Cryptococcus neoformans

R García-Rodas, N Trevijano-Contador… - Frontiers in …, 2015 - frontiersin.org
Cryptococcus neoformans is an opportunistic fungal pathogen that has several well-
described virulence determinants. A polysaccharide capsule and the ability to produce …

The effect of L-DOPA on Cryptococcus neoformans growth and gene expression

HC Eisenman, SK Chow, KK Tsé, E McClelland… - Virulence, 2011 - Taylor & Francis
Cryptococcus neoformans is unusual among melanotic fungi in that it requires an
exogenous supply of precursor to synthesize melanin. C. neoformans melanizes during …

Induction by Klebsiella aerogenes of a Melanin-Like Pigment in Cryptococcus neoformans

S Frases, S Chaskes, E Dadachova… - Applied and …, 2006 - Am Soc Microbiol
While studying the interaction of Cryptococcus neoformans with Dictyostelium discoideum,
we noticed that yeast colonies in agar with a feeder lawn of Klebsiella aerogenes were …

Melanization in Cryptococcus neoformans requires complex regulation

RJB Cordero, E Camacho, A Casadevall - MBio, 2020 - Am Soc Microbiol
The fungal human pathogen Cryptococcus neoformans undergoes melanization in
response to nutrient starvation and exposure to exogenous melanin precursors …

Novel gene functions required for melanization of the human pathogen Cryptococcus neoformans

FJ Walton, A Idnurm, J Heitman - Molecular microbiology, 2005 - Wiley Online Library
The ability to produce melanin is a key virulence factor in many fungal pathogens including
the human basidiomycete pathogen Cryptococcus neoformans, a major cause of life …

Cryptococcus neoformans melanin and virulence: mechanism of action

Y Wang, P Aisen, A Casadevall - Infection and immunity, 1995 - Am Soc Microbiol
Black melanin-like pigments are produced by several neurotropic fungi, including
Cryptococcus neoformans. Pigment production is associated with virulence. In media …

[HTML][HTML] Faster Cryptococcus Melanization Increases Virulence in Experimental and Human Cryptococcosis

HR de Sousa, GP de Oliveira Jr, SO Frazão… - Journal of Fungi, 2022 - mdpi.com
Cryptococcus spp. are human pathogens that cause 181,000 deaths per year. In this work,
we systematically investigated the virulence attributes of Cryptococcus spp. clinical isolates …