Cryptococcus neoformans: life cycle, morphogenesis, and virulence

GJ He, L Zhang, S Ma, H Ding, X Xu, Y Yang… - Molecular Medical …, 2024 - Elsevier
This chapter presents Cryptococcus neoformans, an important model human fungal
pathogen, with a focus on sexual reproduction and morphogenesis given that they play key …

Melanization of Cryptococcus neoformans in murine infection

JD Nosanchuk, P Valadon, M Feldmesser… - … and cellular biology, 1999 - Am Soc Microbiol
Cryptococcus neoformans is a fungus that is pathogenic in humans and that can produce
melanin in vitro. Melanization is associated with virulence, but there is no evidence that …

Melanin Biosynthesis in Cryptococcus neoformans

PR Williamson, K Wakamatsu, S Ito - Journal of bacteriology, 1998 - Am Soc Microbiol
Pigment production by Cryptococcus neoformans is virulence associated. Dopamine-and 3,
4-dihydroxyphenylalanine–melanin products were identified after acidic permanganate …

Molecular Genetic Analyses of Mating Pheromones Reveal Intervariety Mating or Hybridization in Cryptococcus neoformans

V Chaturvedi, J Fan, B Stein, MJ Behr… - Infection and …, 2002 - Am Soc Microbiol
The sexual mating of the pathogenic yeast Cryptococcus neoformans is important for
pathogenesis studies because the fungal virulence is linked to the α mating type (MATα). We …

[图书][B] Melanin and Virulence in Cryptococcus neoformans

Y Wang - 1996 - search.proquest.com
Cryptococcus neoformans is an opportunistic fungal pathogen. C. neoformans has a
phenoloxidase enzyme system which catalyzes black pigment formation from catechol …

The Role of Host Gender in the Pathogenesis of Cryptococcus neoformans Infections

EE McClelland, LM Hobbs, J Rivera, A Casadevall… - PloS one, 2013 - journals.plos.org
Cryptococcus neoformans (Cn) is a pathogenic yeast and the cause of cryptococcal
meningitis. Prevalence of disease between males and females is skewed, with males having …

Life Cycle of Cryptococcus neoformans

Y Zhao, J Lin, Y Fan, X Lin - Annual review of microbiology, 2019 - annualreviews.org
Cryptococcus neoformans is a ubiquitous environmental fungus and an opportunistic
pathogen that causes fatal cryptococcal meningitis. Advances in genomics, genetics, and …

Cryptococcus neoformans mating and virulence are regulated by the G-protein α subunit GPA1 and cAMP

JA Alspaugh, JR Perfect, J Heitman - Genes & development, 1997 - genesdev.cshlp.org
This study explores signal transduction pathways that function during mating and infection in
the opportunistic, human fungal pathogen Cryptococcus neoformans. The gene encoding a …

Formulation of a Defined V8 Medium for Induction of Sexual Development of Cryptococcus neoformans

CR Kent, P Ortiz-Bermúdez, SS Giles… - Applied and …, 2008 - Am Soc Microbiol
For over 3 decades, sexual development in the human fungal pathogen Cryptococcus
neoformans and other fungi has been initiated by growing compatible mating partners on V8 …

Solid-state NMR spectroscopy identifies three classes of lipids in Cryptococcus neoformans melanized cell walls and whole fungal cells

C Chrissian, E Camacho, JE Kelly, H Wang… - Journal of Biological …, 2020 - ASBMB
A primary virulence-associated trait of the opportunistic fungal pathogen Cryptococcus
neoformans is the production of melanin pigments that are deposited into the cell wall and …