The fungus Cryptococcus neoformans is the causative agent of cryptococcosis, a disease
that is uniformly lethal unless treated with antifungal drugs, yet current regimens are …

Cryptococcus gattii and Cryptococcus neoformans are causal agents of cryptococcosis,
which manifests as pneumonia and meningitis. C. gattii has recently received widespread …

Cryptococcus neoformans is an opportunistic fungal pathogen known for its remarkable
ability to infect and subvert phagocytes. This ability provides survival and persistence within …

Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …

Cryptococcus gattii is commonly associated with Eucalyptus spp. and is able to cause
potentially serious disease in immunocompromised humans. As the virulence factors of …

Abstract The 3, 4‐dihydroxyphenylalanine (DOPA) melanin is one of the important virulence
factors for Cryptococcus neoformans, which may trigger immune responses in the host …

Macrophages serve as a first line of defense against infection with the facultative
intracellular pathogen, Cryptococcus neoformans (Cn). However, the ability of these innate …

The pathogenic species of Cryptococcus are a major cause of mortality owing to severe
infections in immunocompromised as well as immunocompetent individuals. Although …

Cryptococcus neoformans MAT α and MAT a pheromones were amplified by direct PCR.
Nucleotide sequence analyses revealed unique restriction enzyme sites. Sixty strains were …

Melanin is an antioxidant polyphenol pigment required for the pathogenicity of many fungal
pathogens, but comprehensive regulatory mechanisms remain unidentified. In this study, we …