[HTML][HTML] The role of mitochondria in oocyte maturation

A Kirillova, JEJ Smitz, GT Sukhikh, I Mazunin - Cells, 2021 - mdpi.com
With the nucleus as an exception, mitochondria are the only animal cell organelles
containing their own genetic information, called mitochondrial DNA (mtDNA). During oocyte …

[HTML][HTML] Embryo and its mitochondria

P May-Panloup, M Boguenet, H El Hachem, PE Bouet… - Antioxidants, 2021 - mdpi.com
The mitochondria, present in almost all eukaryotic cells, produce energy but also contribute
to many other essential cellular functions. One of the unique characteristics of the …

[HTML][HTML] Clinical application of antioxidants to improve human oocyte mitochondrial function: A review

C Rodríguez-Varela, E Labarta - Antioxidants, 2020 - mdpi.com
Mitochondria produce adenosine triphosphate (ATP) while also generating high amounts of
reactive oxygen species (ROS) derived from oxygen metabolism. ROS are small but highly …

Oocyte mitochondria—Key regulators of oocyte function and potential therapeutic targets for improving fertility

D Adhikari, I Lee, WS Yuen, J Carroll - Biology of Reproduction, 2022 - academic.oup.com
The development of oocytes and early embryos is dependent on mitochondrial ATP
production. This reliance on mitochondrial activity, together with the exclusively maternal …

Mitochondrial function in the human oocyte and embryo and their role in developmental competence

J Van Blerkom - Mitochondrion, 2011 - Elsevier
The role of mitochondria as a nexus of developmental regulation in mammalian oogenesis
and early embryogenesis is emerging from basic research in model species and from …

Mitochondrial functions on oocytes and preimplantation embryos

L Wang, D Wang, X Zou, C Xu - Journal of Zhejiang University Science B, 2009 - Springer
Oocyte quality has long been considered as a main limiting factor for in vitro fertilization
(IVF). In the past decade, extensive observations demonstrated that the mitochondrion plays …

[HTML][HTML] Mitochondria: Their relevance during oocyte ageing

J van der Reest, GN Cecchino, MC Haigis… - Ageing Research …, 2021 - Elsevier
The oocyte is recognised as the largest cell in mammalian species and other multicellular
organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and …

[HTML][HTML] Mitochondria in oocyte aging: current understanding

D Zhang, D Keilty, ZF Zhang… - Facts, views & vision in …, 2017 - ncbi.nlm.nih.gov
The oocyte is the largest cell found in multicellular organisms. Mitochondria, as the energy
factories for cells, are found in high numbers in oocytes, as they provide the energy for …

Mitochondrial DNA assessment to determine oocyte and embryo viability

E Fragouli, D Wells - Seminars in reproductive medicine, 2015 - thieme-connect.com
Mitochondria are the key regulators of multiple vital cellular processes, including apoptosis,
calcium homeostasis, and the generation of ATP via the metabolic pathway known as …

The role of mitochondrial function in the oocyte and embryo

R Dumollard, M Duchen, J Carroll - Current topics in developmental …, 2007 - Elsevier
Mitochondria have long been known to be the powerhouses of the cell but they also
contribute to redox and Ca 2+ homeostasis, provide intermediary metabolites and store …